Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893176 | 1.00 | KDM4E (0.59) | KDM4EL3MBTL1KDM4CALOX15NPC1 | |
| SCHEMBL20419488 | 0.83 | KDM4E (0.64) | KDM4EL3MBTL1KDM4CALOX15NPC1 | |
| SCHEMBL29811161 | 0.83 | CA12 (0.50) | KDM4EL3MBTL1NPC1RAB9ACA12 | |
| SCHEMBL7926743 | 0.83 | CA12 (0.50) | KDM4EL3MBTL1NPC1RAB9ACA12 | |
| SCHEMBL31536142 | 0.82 | CA12 (0.49) | L3MBTL1NPC1RAB9ACA12CA1 | |
| SCHEMBL2622774 | 0.82 | CA12 (0.49) | L3MBTL1NPC1RAB9ACA12CA1 | |
| SCHEMBL6575685 | 0.77 | CA12 (0.50) | KDM4EL3MBTL1ALOX15NPC1RAB9A | |
| SCHEMBL29800427 | 0.76 | CA12 (0.56) | L3MBTL1NPC1RAB9ACA12CA1 | |
| SCHEMBL659139 | 0.76 | CA12 (0.56) | KDM4EL3MBTL1NPC1RAB9ACA12 | |
| SCHEMBL27077391 | 0.76 | KDM4E (0.72) | KDM4EL3MBTL1KDM4CALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |
| WO-2000006556-A1 | SUBSTITUTED OXAZOLINES AS ANTIPROLIFERATIVE AGENTS | ABBOTT LABORATORIES (US) | 2000-02-10 | — | — | WO | disclosed |