Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719044 | 0.88 | ALDH1A1 (0.57) | ESR1LMNACYP1A2CYP3A4HDAC1 | |
| SCHEMBL9590536 | 0.85 | RAB9A (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29800427 | 0.85 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL811649 | 0.85 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7744434 | 0.85 | L3MBTL1 (0.64) | ESR1LMNACYP1A2CYP3A4KMT2A | |
| Ethyl Acetate SCHEMBL575043 | 0.84 | MAPK1 (0.53) | LMNAHDAC1HDAC6KMT2AMAPT | |
| SCHEMBL29637478 | 0.84 | MAPK1 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL152572 | 0.84 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30893690 | 0.84 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1971939 | 0.84 | MAPK1 (0.61) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611857-B | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 上海伍夫科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-114195759-B | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 上海零诺生物科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-115611857-A | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 上海伍夫科技有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-114195759-A | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 广州天然科技有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-101514184-A | Synthetic method of 5-bromo-2-methylpyridine | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2009-08-26 | — | — | CN | claimed |
| JP-2096577-A | — | — | None | — | — | JP | disclosed |
| CN-115611857-B | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 上海伍夫科技有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-20230357110-A1 | PROCESS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2023-11-09 | — | — | US | disclosed |
| CN-114195759-B | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 上海零诺生物科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116802184-A | Pyrazolothiazole carboxamides and their use as PDGFR inhibitors | 埃科特莱茵药品有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-114437025-B | Racemization 6-methyl nicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-111566103-B | Aminoimidazopyrazines as kinase inhibitors | 百时美施贵宝公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-0210782-A2 | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-02-04 | — | — | EP | disclosed |
| US-4579953-A | OXIDIZING 2-METHYL-5-ETHYLPYRIDINE, ESTERIFYING WITH AN ALCOHOL | LONZA LTD. (CH) | 1986-04-01 | — | — | US | disclosed |
| US-4127583-A | Preparation of 3-(pyridinyl)-2-cyclohexene-1-ones | STERLING DRUG INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4111946-A | Preparation of 3-(pyridinyl)-2-cyclohexen-1-ones | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4088764-A | CARDIOVASCULAR DISORDERS, BETA-ADRENERGIC BLOCKING AGENTS, ANTIARRHYTHMIC AGENTS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4075217-A | Conversion of 3-(pyridinyl)-2-cyclohexen-1-one to 3-(pyridinyl)anilines | STERLING DRUG INC. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4066768-A | ADRENERGIC BLOCKING AGENTS, ANTIARRHYTHMIC | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |
| US-4026900-A | 3-(Pyridinyl)-2-cyclohexen-1-ones | STERLING DRUG INC. (US) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357110-A1 | PROCESS | HSD17B10, HSD11B1, ADH5 | CA12 276/4885CA1 202/4885CA2 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.