Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674175 | 0.85 | SIGMAR1 (0.45) | HPGD | |
| Hydrochloric Acid SCHEMBL11676386 | 0.84 | SIGMAR1 (0.44) | HPGD | |
| SCHEMBL14458597 | 0.73 | HRH3 (0.50) | HRH3OPRM1OPRD1CHRNA7GAA | |
| SCHEMBL5622289 | 0.73 | HRH3 (0.50) | HRH3OPRM1OPRD1CHRNA7GAA | |
| SCHEMBL5621012 | 0.73 | HRH3 (0.50) | HRH3OPRM1OPRD1CHRNA7GAA | |
| SCHEMBL2847795 | 0.70 | KMT2A (0.36) | GAA | |
| SCHEMBL8541761 | 0.70 | HRH3 (0.73) | HRH3OPRM1OPRD1CHRNA7 | |
| SCHEMBL6312115 | 0.70 | HRH3 (0.73) | HRH3OPRM1OPRD1CHRNA7 | |
| SCHEMBL18831804 | 0.69 | SIGMAR1 (0.54) | HRH3OPRM1OPRD1GAA | |
| SCHEMBL13679488 | 0.67 | FUCA1 (0.46) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248752-B1 | Azabicyclooctane compositions and methods for enhancing chemotherapy | SMITH CHARLES DUANE (US) | 2001-06-19 | — | — | US | claimed |
| US-6248752-B1 | Azabicyclooctane compositions and methods for enhancing chemotherapy | SMITH CHARLES DUANE (US) | 2001-06-19 | — | — | US | disclosed |