Chloromethane

Chloromethane

SCHEMBL7930183

CCP(c1ccccc1)c1ccccc1.CCP(c1ccccc1)c1ccccc1.CCl.[Pd]

nearest known ligand 0.39

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KCNN4 O15554 1/20 0.38
TP53 P04637 1/20 0.36
ESR1 P03372 4/20 0.33
ESR2 Q92731 4/20 0.33
HPGD P15428 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 2/20 0.32
HTT P42858 1/20 0.32
PSIP1 O75475 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
TAAR1 Q96RJ0 2/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8384147 0.95 CYP3A4 (0.43) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL28452303 0.93 CYP3A4 (0.38) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL34614 0.92 CYP3A4 (0.45) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL27863771 0.90 CYP3A4 (0.39) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL1248431 0.90 CYP3A4 (0.39) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL5076037 0.90 CYP3A4 (0.39) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL3397431 0.90 CYP3A4 (0.39) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL28509714 0.90 CYP3A4 (0.39) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL28811253 0.90 CYP3A4 (0.39) CYP3A4TDP1KCNN4TP53ESR1
SCHEMBL3749691 0.90 CYP3A4 (0.43) CYP3A4TDP1KCNN4TP53ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265506-B1 AMORPHOUS COPOLYMERS THE B. F. GOODRICH COMPANY 2001-07-24 US disclosed
EP-0988331-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS THE B.F. GOODRICH COMPANY (US) 2000-03-29 EP disclosed
WO-1998056839-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS THE B.F. GOODRICH COMPANY (US) 1998-12-17 WO disclosed