Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248431 | 1.00 | CYP3A4 (0.39) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL34614 | 0.92 | CYP3A4 (0.45) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL28509714 | 0.90 | CYP3A4 (0.39) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL5076037 | 0.90 | CYP3A4 (0.39) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL27863771 | 0.90 | CYP3A4 (0.39) | CYP3A4TDP1TP53ESR1ESR2 | |
| Chloromethane SCHEMBL7930183 | 0.90 | CYP3A4 (0.39) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL28811253 | 0.90 | CYP3A4 (0.39) | CYP3A4TDP1TP53ESR1ESR2 | |
| Hydrogen Sulfide SCHEMBL8154468 | 0.90 | TDP1 (0.43) | CYP3A4TDP1TP53ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL11570696 | 0.90 | CYP3A4 (0.43) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL3749691 | 0.90 | CYP3A4 (0.43) | CYP3A4TDP1TP53ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813452-A | Method for preparing dihydro-honokiol | 济南明微医药科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-115838349-B | Preparation method of 3- (7-cyano-5- (2-oxo propyl) indoline-1-yl) propyl benzoate | 南京桦冠生物技术有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-114195687-B | Beta-chloro tetra-substituted alkenyl sulfone compound and synthesis method thereof | 华南理工大学 | 2023-06-20 | — | — | CN | claimed |
| CN-113666883-B | Method for synthesizing 4-vinyl isoxazole derivative | 华南理工大学 | 2023-06-16 | — | — | CN | claimed |
| CN-115894492-B | Preparation method of diquat dichloride | 安徽红太阳生物化学有限公司 | 2023-06-16 | — | — | CN | claimed |
| CN-115894492-A | Preparation method of diquat dichloride | 安徽红太阳生物化学有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115838349-A | Preparation method of 3- (7-cyano-5- (2-oxopropyl) indolin-1-yl) propyl benzoate | 南京桦冠生物技术有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115768763-A | Preparation method of CDK4/6 inhibitor | 正大天晴药业集团股份有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-111484491-B | Substituted pyrido-cyclic compounds, process for their preparation and their use | 四川科伦博泰生物医药股份有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114195687-A | Beta-chloro tetra-substituted alkenyl sulfone compound and synthetic method thereof | 华南理工大学 | 2022-03-18 | — | — | CN | claimed |
| CN-109988145-B | Preparation method of vinyl sulfate | 福建博鸿新能源科技有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-108912020-B | Preparation method of Orobactit and intermediate thereof | 上海博志研新药物技术有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-111484491-A | Substituted pyrido-cyclic compounds, process for their preparation and their use | 四川科伦博泰生物医药股份有限公司 | 2020-08-04 | — | — | CN | claimed |
| CN-106910899-B | Preparation method of nitrogen-doped double-shell structure nano catalyst | 广西大学 | 2020-07-03 | — | — | CN | claimed |
| CN-108147999-B | The preparation method of dexmedetomidine hydrochloride and its intermediate | 上海博志研新药物技术有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-108147999-A | The preparation method of dexmedetomidine hydrochloride and its intermediate | 上海博志研新药物技术有限公司 | 2018-06-12 | — | — | CN | claimed |
| CN-102951979-A | Preparation method of 2-substitutional vinyl alcohol formate derivative | UNIV TIANJIN | 2013-03-06 | — | — | CN | claimed |
| CN-102746225-A | Preparation method of 2-alkyl-3,4-disubstituted isoquinolyl-1(2H)-ketone derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | claimed |
| CN-102746224-A | Preparation method of 2-aryl-3,4-disubstituted isoquinolyl-1(2H)-ketone derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | claimed |
| CN-117917406-A | Heterocyclic compounds, process for their preparation and their use | 四川科伦博泰生物医药股份有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-117800976-A | Nitrogen-containing heterocyclic compound, preparation method and application | 上海凌达生物医药有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-113527299-B | Nitrogen-containing condensed ring compound, preparation method and application | 上海凌达生物医药有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-114907350-B | Nitrogen-containing condensed ring compound, preparation method and application | 上海凌达生物医药有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117304102-A | Preparation method of quinolinone derivative | 正大天晴药业集团股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117177979-A | Cyclic dibenzyl tetrahydroisoquinoline compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-12-05 | — | — | CN | disclosed |
| CN-113563323-B | Benzothiazolyl biaryl compound, preparation method and application | 上海凌达生物医药有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-113061132-B | Condensed ring lactam compound, preparation method and application | 上海凌达生物医药有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-116891465-A | N-substituted quinolinone compounds, preparation method and application thereof | 苏州旺山旺水生物医药有限公司 | 2023-10-17 | — | — | CN | disclosed |
| WO-2023186023-A1 | N-SUBSTITUTED QUINOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州旺山旺水生物医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |
| CN-114075196-B | Aromatic ring lactam compound, preparation method and application thereof | 上海凌达生物医药有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116635392-A | Substituted azabicyclooctane compounds, intermediates thereof and methods of making | 上海海雁医药科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116574104-A | Biaryl benzylamine compound, preparation method and application | 如东凌达生物医药科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-11718584-B2 | Process for the synthesis anthranilic diamide compounds and intermediates thereof | PI INDUSTRIES LTD. (IN) | 2023-08-08 | — | — | US | disclosed |
| CN-116444427-A | Diaryl compounds for tubulin-SRC double-target inhibitor | 武汉人福创新药物研发中心有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-116425796-A | Pyrimidine heterocyclic compounds, preparation method and application | 如东凌达生物医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-115838349-B | Preparation method of 3- (7-cyano-5- (2-oxo propyl) indoline-1-yl) propyl benzoate | 南京桦冠生物技术有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114195687-B | Beta-chloro tetra-substituted alkenyl sulfone compound and synthesis method thereof | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-113666883-B | Method for synthesizing 4-vinyl isoxazole derivative | 华南理工大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-115894492-B | Preparation method of diquat dichloride | 安徽红太阳生物化学有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115894492-B | Preparation method of diquat dichloride | 安徽红太阳生物化学有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-114127053-B | Substituted pyrazine compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-116253740-A | Cyclic dibenzyl isoquinoline compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-13 | — | — | CN | disclosed |
| CN-116239474-A | Preparation method of indacaterol intermediate 5, 6-diethyl-2, 3-dihydro-1H-indene-2-amine hydrochloride | 石家庄手性化学有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-20230174526-A1 | BENZOTHIAZOLYL BIARYL COMPOUND, AND PREPARATION METHOD AND USE | SHANGHAI RINGENE THERAPEUTICS CO. LTD (CN) | 2023-06-08 | — | — | US | disclosed |
| CN-116143805-A | Nitrogen-containing heterocyclic biaryl compounds, preparation method and application | 上海凌达生物医药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116143806-A | Nitrogen-containing heterocyclic compound, preparation method and application | 上海凌达生物医药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-115960098-A | Preparation method and application of nitrogen-containing fused ring compounds | 上海凌达生物医药有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115894492-A | Preparation method of diquat dichloride | 安徽红太阳生物化学有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115894492-A | Preparation method of diquat dichloride | 安徽红太阳生物化学有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115838349-A | Preparation method of 3- (7-cyano-5- (2-oxopropyl) indolin-1-yl) propyl benzoate | 南京桦冠生物技术有限公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-4144732-A1 | BENZOTHIAZOLYL BIARYL COMPOUND, AND PREPARATION METHOD AND USE | Shanghai Ringene BioPharma Co., Ltd. (CN) | 2023-03-08 | — | — | EP | disclosed |
| CN-115768763-A | Preparation method of CDK4/6 inhibitor | 正大天晴药业集团股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115667239-A | Substituted pyrazines, pharmaceutical compositions comprising them and their use | 四川科伦博泰生物医药股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-110016026-B | Pyrimidopyridone compounds with antitumor activity, preparation method and application | 上海凌济生物科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-113185472-B | Method for synthesizing 4-alkoxy alkenyl isoxazole derivative | 华南理工大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-110835310-B | Intermediate, preparation method and application | 南京中硼联康医疗科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-111484491-B | Substituted pyrido-cyclic compounds, process for their preparation and their use | 四川科伦博泰生物医药股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-112480107-B | Substituted azabicyclooctane compounds, intermediates therefor and processes for their preparation | 上海海雁医药科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907350-A | Nitrogen-containing condensed ring compounds, preparation method and application | 上海凌达生物医药有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-113214119-B | Selective addition method of dienamine and phenylboronic acid controlled by small steric hindrance | 山东理工大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-112010859-B | Fused ring compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-07-19 | — | — | CN | disclosed |
| CN-114685487-A | Pyrimidine heterocyclic compound, preparation method and application | 上海凌达生物医药有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-111763217-B | Thieno-nitrogen heterocyclic compounds, preparation method and application | 上海凌达生物医药有限公司 | 2022-06-28 | — | — | CN | disclosed |
| US-20220185782-A1 | A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF | PI INDUSTRIES LTD. (IN) | 2022-06-16 | — | — | US | disclosed |
| CN-110835352-B | Preparation method18Process for F-BPA | 南京中硼联康医疗科技有限公司 | 2022-05-24 | — | — | CN | disclosed |
| US-20220127271-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC SHP2 INHIBITOR COMPOUND, PREPARATION METHOD, AND USE | SHANGHAI RINGENE BIOPHARMA CO., LTD. (CN) | 2022-04-28 | — | — | US | disclosed |
| CN-114375293-A | Isoquinoline compounds and preparation method and application thereof | 中国科学院上海药物研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-109384780-B | Tetrahydro-protoberberine compounds, preparation method, application and pharmaceutical composition thereof | 中国科学院上海药物研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-111704610-B | Pyrrolylamido pyridone compounds, preparation method and application | 上海凌达生物医药有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114195804-A | Piperidine condensed ring compound, preparation method and application | 上海凌达生物医药有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195687-A | Beta-chloro tetra-substituted alkenyl sulfone compound and synthetic method thereof | 华南理工大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-111057048-B | Aminopyrazine/pyridine compound, preparation method and application | 上海凌达生物医药有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114181257-A | Pyridine compound, pharmaceutical composition containing pyridine compound, preparation method and application of pyridine compound | 四川科伦博泰生物医药股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-114127053-A | Substituted pyrazine compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114075196-A | Aromatic ring-lactam compound, preparation method and application thereof | 上海凌达生物医药有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-112457326-B | Aromatic heterocyclic lactam compound, preparation method and application | 上海凌达生物医药有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-111153901-B | Nitrogen-containing fused heterocyclic SHP2 inhibitor compound, preparation method and application | 上海凌达生物医药有限公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-111704611-B | Aryl spiro SHP2 inhibitor compound, preparation method and application | 上海凌达生物医药有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-112300194-B | Condensed ring pyridone compounds, preparation method and application | 上海凌达生物医药有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-107266451-B | Preparation method of rebuximab intermediate | 上海医药工业研究院 | 2021-12-31 | — | — | CN | disclosed |
| EP-3927685-A1 | A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF | PI Industries Ltd. (IN) | 2021-12-29 | — | — | EP | disclosed |
| CN-112094269-B | Saturated six-membered ring heterocyclic compound, preparation method and application | 上海凌达生物医药有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-113614063-A | Method for synthesizing anthranilamide compound and intermediate thereof | PI工业有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-110857300-B | Condensed ring triazole compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113563323-A | Benzothiazolyl biaryl compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113527299-A | Nitrogen-containing condensed ring compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-10-22 | — | — | CN | disclosed |
| EP-3184521-B1 | INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITORS, PREPARATION AND USE THEREOF | SHANGHAI HAIHE PHARMACEUTICAL CO LTD (CN) | 2021-10-06 | — | — | EP | disclosed |
| CN-112300173-B | Nitrogen-containing polycyclic compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-112142735-B | Condensed cyanopyridine compound, preparation method and application | 上海凌达生物医药有限公司 | 2021-09-17 | — | — | CN | disclosed |
| EP-3878853-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC SHP2 INHIBITOR COMPOUND, PREPARATION METHOD, AND USE | Shanghai Ringene BioPharma Co., Ltd. (CN) | 2021-09-15 | — | — | EP | disclosed |
| CN-110950876-B | Furanolactam compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-110964012-B | Fused heterocyclic biaryl benzyl alcohol compound, preparation method and application | 上海凌达生物医药有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-113214119-A | Selective addition method of dienamine and phenylboronic acid controlled by small steric hindrance | 山东理工大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-107614502-B | Preparation and application of kinase inhibitor | 常州隆赛医药科技有限公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-113061132-A | Condensed ring lactam compound, preparation method and application | 上海凌达生物医药有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-109988145-B | Preparation method of vinyl sulfate | 福建博鸿新能源科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-108912020-B | Preparation method of Orobactit and intermediate thereof | 上海博志研新药物技术有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-109721600-B | Nitrogen-containing fused ring compounds and preparation method and application thereof | 上海凌达生物医药有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-112480107-A | Substituted azabicyclooctane compounds, intermediates therefor and processes for their preparation | 上海海雁医药科技有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-112457326-A | Aromatic heterocyclic lactam compound, preparation method and application | 上海凌达生物医药有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-107922405-B | Compound with ERK kinase inhibitory activity, preparation method and application thereof | 中国科学院上海药物研究所 | 2021-02-19 | — | — | CN | disclosed |
| CN-112300196-A | Piperidine condensed ring compound, preparation method and application | 上海凌达生物医药有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112300194-A | Condensed ring pyridone compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112142735-A | Condensed cyanopyridine compound, preparation method and application | 上海凌达生物医药有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-112094269-A | Saturated six-membered ring heterocyclic compound, preparation method and application | 上海凌达生物医药有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-109721599-B | Amino-substituted nitrogen-containing fused ring compound and preparation method and application thereof | 上海凌达生物医药有限公司 | 2020-12-15 | — | — | CN | disclosed |
| WO-2020239073-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-03 | — | — | WO | disclosed |
| CN-112010859-A | Fused ring compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-12-01 | — | — | CN | disclosed |
| CN-111763217-A | Thieno-nitrogen heterocyclic compound, preparation method and application | 上海凌达生物医药有限公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-111704611-A | Aryl spiro SHP2 inhibitor compound, preparation method and application | 上海凌达生物医药有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111704610-A | Pyrrolylamido pyridone compounds, preparation method and application | 上海凌达生物医药有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-106146515-B | Preparation and application of novel kinase inhibitor | 常州隆赛医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111499514-A | Preparation method of intermediate of roxasistat | 连云港润众制药有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111484491-A | Substituted pyrido-cyclic compounds, process for their preparation and their use | 四川科伦博泰生物医药股份有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-107722145-B | Preparation method of hydrogenated nitrile rubber | 中国石油化工股份有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-108147972-B | Preparation method of vipatavir intermediate and analogue thereof | 成都西岭源药业有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-106910899-B | Preparation method of nitrogen-doped double-shell structure nano catalyst | 广西大学 | 2020-07-03 | — | — | CN | disclosed |
| CN-107722147-B | Selective hydrogenation method of polar polymer | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-111153901-A | Nitrogen-containing fused heterocyclic SHP2 inhibitor compound, preparation method and application | 如东凌达生物医药科技有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-111057048-A | Aminopyrazine/pyridine compound, preparation method and application | 如东凌达生物医药科技有限公司 | 2020-04-24 | — | — | CN | disclosed |
| CN-110964012-A | Fused heterocyclic biaryl benzyl alcohol compound, preparation method and application | 如东凌达生物医药科技有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-110950876-A | Furanolactam compounds, preparation method and application | 如东凌达生物医药科技有限公司 | 2020-04-03 | — | — | CN | disclosed |
| WO-2020063976-A1 | FUSED HETEROCYCLIC BIARYL BENZYL ALCOHOL COMPOUND, PREPARATION METHOD, AND USE | 如东凌达生物医药科技有限公司 | 2020-04-02 | — | — | WO | disclosed |
| CN-110857300-A | Condensed ring triazole compounds, preparation method and application | 如东凌达生物医药科技有限公司 | 2020-03-03 | — | — | CN | disclosed |
| WO-2020038458-A1 | CLASS OF FUSED RING TRIAZOLE COMPOUND, PREPARATION METHOD, AND USE | 如东凌达生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |
| CN-110835352-A | Preparation method18Process for F-BPA | 南京中硼联康医疗科技有限公司 | 2020-02-25 | — | — | CN | disclosed |
| CN-110835310-A | Intermediate, preparation method and application | 南京中硼联康医疗科技有限公司 | 2020-02-25 | — | — | CN | disclosed |
| WO-2020035011-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | 南京中硼联康医疗科技有限公司 | 2020-02-20 | — | — | WO | disclosed |
| US-10562900-B2 | Indazole compounds as FGFR kinase inhibitor, preparation and use thereof | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2020-02-18 | — | — | US | disclosed |
| CN-106132956-B | Heterocyclic compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2019-12-10 | — | — | CN | disclosed |
| EP-3284746-B1 | PREPARATION AND USE OF KINASE INHIBITOR | CHANGZHOU LONGTHERA PHARMACEUTICALS INC (CN) | 2019-07-03 | — | — | EP | disclosed |
| US-10308654-B2 | Preparation and use of kinase inhibitor | CHANGZHOU LONGTHERA PHARMACEUTICALS INC. (CN) | 2019-06-04 | — | — | US | disclosed |
| US-20180346467-A9 | PREPARATION AND USE OF KINASE INHIBITOR | CHANGZHOU LONGTHERA PHAMACEUTICALS INC (CN) | 2018-12-06 | — | — | US | disclosed |
| US-20180127419-A1 | PREPARATION AND USE OF KINASE INHIBITOR | CHANGZHOU LONGTHERA PHAMACEUTICALS INC (CN) | 2018-05-10 | — | — | US | disclosed |
| EP-3284746-A1 | PREPARATION AND USE OF KINASE INHIBITOR | Changzhou Longthera Pharmaceuticals Inc (CN) | 2018-02-21 | — | — | EP | disclosed |
| US-20170275291-A1 | INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITOR, PREPARATION AND USE THEREOF | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2017-09-28 | — | — | US | disclosed |
| EP-3184521-A1 | INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITOR, PREPARATION AND USE THEREOF | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2017-06-28 | — | — | EP | disclosed |
| CN-106146515-A | The preparation of Azaindole kinase inhibitors and application | 常州隆赛医药科技有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-106132956-A | Heterocyclic compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2016-11-16 | — | — | CN | disclosed |
| EP-2246356-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL CO (JP) | 2013-04-03 | — | — | EP | disclosed |
| CN-102951979-A | Preparation method of 2-substitutional vinyl alcohol formate derivative | UNIV TIANJIN | 2013-03-06 | — | — | CN | disclosed |
| CN-102746224-A | Preparation method of 2-aryl-3,4-disubstituted isoquinolyl-1(2H)-ketone derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | disclosed |
| CN-102746225-A | Preparation method of 2-alkyl-3,4-disubstituted isoquinolyl-1(2H)-ketone derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | disclosed |
| CN-102285937-A | Method for synthesizing febuxostat | — | 2011-12-21 | — | — | CN | disclosed |
| US-20110054171-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2246356-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINES | Sumitomo Chemical Company, Limited (JP) | 2010-11-03 | — | — | EP | disclosed |
| EP-2049535-A1 | ALPHA-CARBOLINE DERIVATIVES AND METHODS FOR PREPARATION THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008016184-A1 | ALPHA-CARBOLINE DERIVATIVES AND METHODS FOR PREPARATION THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-07 | — | — | WO | disclosed |
| WO-2007129268-A2 | IMPROVED PROCESS FOR THE SYNTHESIS OF COQ10 | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007129268-A2 | IMPROVED PROCESS FOR THE SYNTHESIS OF COQ10 | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718584-B2 | Process for the synthesis anthranilic diamide compounds and intermediates thereof | DAO, DDC, QDPR | CYP3A4 44/4885TDP1 4302/4885TP53 1851/4885 |
| US-10562900-B2 | Indazole compounds as FGFR kinase inhibitor, preparation and use thereof | FGFR1, FGFR2, FGFR3 | CYP3A4 356/4885TDP1 2576/4885TP53 1257/4885 |
| US-20220185782-A1 | A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF | DAO, DDC, QDPR | CYP3A4 45/4885TDP1 4313/4885TP53 1763/4885 |
| US-20180127419-A1 | PREPARATION AND USE OF KINASE INHIBITOR | MAP3K19, MAP3K20, MAP3K1 | CYP3A4 3609/4885TDP1 1407/4885TP53 1559/4885 |
| US-20180346467-A9 | PREPARATION AND USE OF KINASE INHIBITOR | MAP3K19, MAP3K20, MAP3K1 | CYP3A4 3609/4885TDP1 1407/4885TP53 1559/4885 |
| US-20230174526-A1 | BENZOTHIAZOLYL BIARYL COMPOUND, AND PREPARATION METHOD AND USE | KRAS, NRAS, HRAS | CYP3A4 395/4885TDP1 1983/4885TP53 8/4885 |
| US-20110054171-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINES | TYR, ARSA, ODC1 | CYP3A4 745/4885TDP1 2919/4885TP53 4368/4885 |
| US-20170275291-A1 | INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITOR, PREPARATION AND USE THEREOF | FGFR1, FGFR2, FGFR3 | CYP3A4 356/4885TDP1 2576/4885TP53 1257/4885 |
| US-10308654-B2 | Preparation and use of kinase inhibitor | MAP3K19, MAP3K20, MAP3K1 | CYP3A4 3609/4885TDP1 1407/4885TP53 1559/4885 |
| US-20220127271-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC SHP2 INHIBITOR COMPOUND, PREPARATION METHOD, AND USE | PTPN1, PTPN7, PTPN9 | CYP3A4 2284/4885TDP1 3328/4885TP53 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.