Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.46 |
| ▸ | TUBB | P07437 | 4/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572868 | 0.83 | BLM (0.62) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL1572866 | 0.83 | BLM (0.62) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| Potassium Ion SCHEMBL28412864 | 0.80 | MAPT (0.47) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL11706382 | 0.80 | MAPK1 (0.50) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL28639889 | 0.77 | MAPT (0.49) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL18287920 | 0.76 | MAPT (0.56) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL2040575 | 0.75 | CES2 (0.56) | MAPTMAPK1BLMNPSR1TSHR | |
| SCHEMBL8115552 | 0.74 | MAPT (0.56) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL8824090 | 0.74 | BLM (0.64) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| Dimethylformamide SCHEMBL28191620 | 0.74 | BLM (0.51) | MAPTL3MBTL1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |