SCHEMBL7930221

SCHEMBL7930221

CCCCC(c1ccc(Cc2ccc(N)cc2)cc1)c1ccc(Cc2ccc(N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 1/20 0.43
CYP19A1 P11511 3/20 0.42
HTR2A P28223 4/20 0.41
HRH1 P35367 2/20 0.38
CYP17A1 P05093 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
MAOB P27338 3/20 0.37
BDKRB2 P30411 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
GFER P55789 1/20 0.35
MAOA P21397 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092737 1.00 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL8095645 1.00 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL8098205 0.95 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL7929681 0.95 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL8094474 0.95 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL8086249 0.93 ALDH1A1 (0.47) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL8092529 0.93 ALDH1A1 (0.47) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL8093807 0.93 ALDH1A1 (0.47) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL8101526 0.93 ALDH1A1 (0.47) CYP3A4ALDH1A1TSHRTDP1MAPT
SCHEMBL8102192 0.93 ALDH1A1 (0.47) CYP3A4ALDH1A1TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1064329-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2001-01-03 EP disclosed
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
WO-1999033923-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed
US-5807961-A Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element using the formers CHISSO CORPORATION (JP) 1998-09-15 US disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed