SCHEMBL7930260

SCHEMBL7930260

O=P(c1ccccc1)(c1ccccc1)C1CCCCC1.c1ccc(P(c2ccccc2)C2CCCCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
GAA P10253 1/20 0.44
KCNA5 P22460 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778610 0.85 SMN1; SMN2 (0.52) SMN1; SMN2GAAKCNA5
SCHEMBL13321940 0.83 GAA (0.53) SMN1; SMN2GAAKCNA5
SCHEMBL301069 0.81 CYP3A4 (0.38) SMN1; SMN2GAA
SCHEMBL34871 0.81 CYP3A4 (0.38) SMN1; SMN2GAA
SCHEMBL13456274 0.81 CYP3A4 (0.38) SMN1; SMN2GAA
SCHEMBL301035 0.81 CYP3A4 (0.38) SMN1; SMN2GAA
Hydrochloric Acid SCHEMBL1582528 0.79 IDO1 (0.36) SMN1; SMN2GAA
Hydrochloric Acid SCHEMBL1582526 0.79 IDO1 (0.36) SMN1; SMN2GAA
SCHEMBL9202452 0.79 CYP3A4 (0.36) SMN1; SMN2GAA
SCHEMBL9634685 0.79 CYP3A4 (0.36) SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827493-B1 PREPARATION OF ARALKANOIC ACIDS AND ESTERS USING MIXED LIGAND CATALYST ALBEMARLE CORP (US) 2001-07-11 EP disclosed
US-5902898-A CARBOXYLATION OF AN ARALKENE WITH CARBON MONOXIDE AND WATER OR AN ALCOHOL IN THE ABSENCE OF OXYGEN AND IN THE PRESENCE OF PALLADIUM-GROUP 6A LIGAND CATALYST ALBEMARLE CORPORATION (US) 1999-05-11 US disclosed