SCHEMBL778610

SCHEMBL778610

O=P(c1ccccc1)(c1ccccc1)C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.52
GAA P10253 3/20 0.52
KCNA5 P22460 1/20 0.40
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
NPSR1 Q6W5P4 3/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 3/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
CFTR P13569 1/20 0.35
ALDH1A1 P00352 3/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALPG P10696 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13321940 0.98 GAA (0.53) SMN1; SMN2GAAKCNA5CA2CA4
SCHEMBL28318624 0.93 SMN1; SMN2 (0.53) SMN1; SMN2GAAKCNA5CA2CA4
SCHEMBL20195697 0.89 HPGD (0.44) SMN1; SMN2GAAKCNA5HPGDCYP3A4
SCHEMBL10426380 0.89 SMN1; SMN2 (0.52) SMN1; SMN2GAAKCNA5CA2CA4
SCHEMBL7930260 0.85 SMN1; SMN2 (0.44) SMN1; SMN2GAAKCNA5
SCHEMBL778386 0.83 SMN1; SMN2 (0.43) SMN1; SMN2GAACA2CA4CA5A
SCHEMBL9927225 0.83 SMN1; SMN2 (0.47) SMN1; SMN2GAAKCNA5CA2CA4
SCHEMBL778410 0.82 GAA (0.41) SMN1; SMN2GAAKCNA5CA2CA4
SCHEMBL11991127 0.81 SMN1; SMN2 (0.41) SMN1; SMN2GAAKCNA5ALDH1A1
SCHEMBL24817133 0.81 SMN1; SMN2 (0.42) SMN1; SMN2GAAKCNA5CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4108706-B1 METHOD FOR PRODUCING CYCLIC POLYSILOXANE SHINETSU CHEMICAL CO (JP) 2025-09-10 EP claimed
CN-118406027-A Preparation method of trans-2, 5-dimethyl tetrahydrofuran 南昌大学 2024-07-30 CN claimed
CN-115135698-B Process for producing cyclic polysiloxane 信越化学工业株式会社 2024-04-26 CN claimed
CN-115608359-B Copper catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2024-04-05 CN claimed
CN-117085698-A Mercury-free catalyst with ultralow noble metal content for hydrochlorination of acetylene and preparation method thereof 中国科学院大连化学物理研究所 2023-11-21 CN claimed
CN-115873402-A Heat-resistant master batch and heat-stable polyamide composition thereof 华峰集团有限公司 2023-03-31 CN claimed
US-20230095953-A1 METHOD FOR PRODUCING CYCLIC POLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-03-30 US claimed
CN-115608359-A Copper catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2023-01-17 CN claimed
EP-4108706-A1 METHOD FOR PRODUCING CYCLIC POLYSILOXANE Shin-Etsu Chemical Co., Ltd. (JP) 2022-12-28 EP claimed
CN-115135698-A Method for producing cyclic polysiloxane 信越化学工业株式会社 2022-09-30 CN claimed
US-10815258-B2 Phosphine oxides reduction RHODIA OPERATIONS (FR) 2020-10-27 US claimed
US-20200231613-A1 PHOSPHINE OXIDES REDUCTION SPECIALTY OPERATIONS FRANCE (FR) 2020-07-23 US claimed
US-4155932-A REACTING CHLORINE AND CARBON MONOXIDE WITH A TERTIARY PHOSPHINE OXIDE UBE INDUSTRIES, INC. (JP) 1979-05-22 US claimed
EP-4108706-B1 METHOD FOR PRODUCING CYCLIC POLYSILOXANE SHINETSU CHEMICAL CO (JP) 2025-09-10 EP disclosed
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 US disclosed
CN-119101083-A Preparation method and application of cuprous halide-based fluorescent light-emitting material 华东师范大学 2024-12-10 CN disclosed
US-20060133978-A1 Method of making crystalline inorganic particles GENERAL ELECTRIC COMPANY 2006-06-22 US disclosed
US-20040253174-A1 Method of making oxide particles GENERAL ELECTRIC COMPANY 2004-12-16 US disclosed
US-4845306-A PHOSPHINE-RHODIUM CATALYSTS, HYDROFORMYLATION REACTIONS EASTMAN KODAK COMPANY (US) 1989-07-04 US disclosed
US-4155932-A REACTING CHLORINE AND CARBON MONOXIDE WITH A TERTIARY PHOSPHINE OXIDE UBE INDUSTRIES, INC. (JP) 1979-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815258-B2 Phosphine oxides reduction PHOSPHO1, PSPH, PTEN SMN1; SMN2 2237/4885GAA 4214/4885KCNA5 3691/4885
US-20230095953-A1 METHOD FOR PRODUCING CYCLIC POLYSILOXANE POLL, PCNA, RPN1 SMN1; SMN2 4365/4885GAA 3821/4885KCNA5 2475/4885
US-20200231613-A1 PHOSPHINE OXIDES REDUCTION PHOSPHO1, PSPH, PTEN SMN1; SMN2 2237/4885GAA 4214/4885KCNA5 3691/4885
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 SMN1; SMN2 3862/4885GAA 2692/4885KCNA5 394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.