Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932081 | 0.94 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL7538338 | 0.91 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL7933827 | 0.90 | EDNRA (0.83) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL4197810 | 0.87 | EDNRA (1.00) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL8734573 | 0.87 | EDNRA (1.00) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL1028671 | 0.87 | EDNRA (1.00) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL29550762 | 0.87 | EDNRA (1.00) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL7532946 | 0.87 | EDNRA (0.98) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL6953911 | 0.87 | EDNRA (0.98) | EDNRAEDNRB | |
| Sb-209670 SCHEMBL7664400 | 0.87 | EDNRA (0.98) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274737-B1 | CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2001-08-14 | — | — | US | disclosed |
| US-6271399-B1 | METHYL 3-(3,4-METHYLENEDIOXYPHENYL)-6-(PROP-1-YLOXY)-INDANE-2-CARBOXYLATE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION | 2001-08-07 | — | — | US | disclosed |
| US-5817693-A | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORPORATION | 1998-10-06 | — | — | US | disclosed |
| US-5719183-A | HYPOTENSIVE AGENTS; KIDNEY DISEASES; ANTIISCHEMIC AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| US-5719182-A | TREATING HYPERTENSION, RENAL FAILURE, CEREBROVASCULAR DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |