Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12216357 | 0.75 | MAPK1 (0.77) | MAPTSMN1; SMN2TSHRCYP3A4CYP2C19 | |
| SCHEMBL4206188 | 0.74 | MAPT (0.73) | MAPTSMN1; SMN2TSHRGAAHTT | |
| SCHEMBL4209124 | 0.73 | MAPT (0.67) | MAPTSMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL15931634 | 0.71 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2TSHRGAAHTT | |
| SCHEMBL15986500 | 0.71 | MAPT (1.00) | MAPTSMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL4205558 | 0.71 | ALDH1A1 (0.72) | MAPTSMN1; SMN2TSHRGAAHTT | |
| SCHEMBL24716653 | 0.71 | TSHR (0.64) | MAPTSMN1; SMN2TSHRGAAHTT | |
| SCHEMBL30211098 | 0.71 | MAPT (0.80) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL4201282 | 0.69 | KMT2A (0.72) | MAPTSMN1; SMN2TSHRGAAHTT | |
| SCHEMBL13167282 | 0.69 | TP53 (1.00) | MAPTSMN1; SMN2TSHRNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245817-B1 | NEUROPEPTIDE Y | BAYER CORPORATION | 2001-06-12 | — | — | US | claimed |