Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.61 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928661 | 0.94 | CTSB (0.70) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL7925351 | 0.94 | CTSB (0.57) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL7927888 | 0.93 | CTSB (0.54) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL7926981 | 0.92 | CTSB (0.54) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL7921742 | 0.90 | CTSB (0.58) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL7919017 | 0.89 | CTSB (0.48) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL7923951 | 0.86 | CTSB (0.49) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL2431706 | 0.86 | CTSB (0.71) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL2425065 | 0.86 | CTSB (0.71) | CTSBCTSSADRB3ADRA2BADRA2C | |
| SCHEMBL2431712 | 0.86 | CTSB (0.71) | CTSBCTSSADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033466-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C PROTEASE | PHENOMIX CORPORATION (US) | 2010-03-25 | — | — | WO | disclosed |