SCHEMBL7930460

SCHEMBL7930460

CCOC(=O)C1(C)CO[C](C)O1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.45
POLB P06746 1/20 0.37
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
GLA P06280 1/20 0.35
KMT2A Q03164 3/20 0.34
ALOX15 P16050 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 2/20 0.34
MAPK1 P28482 2/20 0.34
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.33
BRD4 O60885 1/20 0.33
PSEN1 P49768 3/20 0.33
ABCB11 O95342 1/20 0.33
LMNA P02545 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7931267 0.85 PSEN1 (0.44) ATMPOLBALDH1A1L3MBTL1HPGD
SCHEMBL28451660 0.84 ATM (0.47) ATMPOLBMAPTALDH1A1GLA
SCHEMBL9206727 0.77
SCHEMBL26830530 0.69 ATM (0.42) ATMPOLBMAPTALDH1A1KMT2A
SCHEMBL12951616 0.69 ALDH1A1 (0.41) ATMPOLBALDH1A1ALOX15HSD17B10
SCHEMBL663919 0.69 ATM (0.50) ATMPOLBMAPTALDH1A1KMT2A
SCHEMBL1868349 0.68 ATM (0.41) ATMPOLBMAPTALDH1A1KMT2A
SCHEMBL12461587 0.68 TP53 (0.38) ATMPOLBMAPTALDH1A1GLA
SCHEMBL7929034 0.68 ATM (0.38) ATMPOLBMAPTALDH1A1GLA
SCHEMBL19508664 0.68 ATM (0.53) ATMPOLBMAPTALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031865-A1 Substituted 3-phenyluracils KLINTZ RALF (DE) 2001-10-18 US disclosed
US-6239074-B1 HERBICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-05-29 US disclosed
EP-0604491-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF Aktiengesellschaft (DE) 1994-07-06 EP disclosed
WO-1993006090-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031865-A1 Substituted 3-phenyluracils CCR1, CCR6, CCR3 ATM 1300/4885POLB 2127/4885MAPT 4647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.