Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.59 |
| ▸ | LMNA | P02545 | 7/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493445 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL12225999 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL7924266 | 0.74 | ALDH1A1 (0.59) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL1612621 | 0.74 | ALDH1A1 (0.57) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL15337542 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL7924134 | 0.72 | ALDH1A1 (0.54) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL12225983 | 0.72 | ALDH1A1 (0.76) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL1493421 | 0.70 | ALDH1A1 (0.59) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL1493311 | 0.70 | ALDH1A1 (0.76) | ALDH1A1LMNAHTTTSHRTP53 | |
| SCHEMBL3455005 | 0.70 | ALDH1A1 (0.60) | ALDH1A1LMNAHTTTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034003-A2 | BENZYLTHIOTETRAZOLE INHIBITORS OF STORE OPERATED CALCIUM RELEASE | CALCIMEDICA, INC. (US) | 2010-03-25 | — | — | WO | disclosed |