SCHEMBL7930568

SCHEMBL7930568

CCCOc1cc(C(=O)OCC)cc(OCCC)c1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA7 P43166 3/20 0.51
CA9 Q16790 3/20 0.51
CA14 Q9ULX7 3/20 0.51
CYP1A2 P05177 4/20 0.50
CYP3A4 P08684 2/20 0.50
MAOA P21397 2/20 0.50
LMNA P02545 2/20 0.50
CYP2D6 P10635 3/20 0.49
SCN1A P35498 3/20 0.49
SCN2A Q99250 3/20 0.49
SCN3A Q9NY46 3/20 0.49
KCNH2 Q12809 2/20 0.49
HRH3 Q9Y5N1 2/20 0.49
CYP2C19 P33261 1/20 0.49
SIGMAR1 Q99720 1/20 0.49
NPC1 O15118 1/20 0.47
HSD17B2 P37059 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928303 0.92 ESR1 (0.54) CA12CA1CA2CA7CA9
SCHEMBL1121160 0.90 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL28201667 0.87 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL7930563 0.85 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL7930668 0.83 HSD17B2 (0.61) CA12CA1CA2CA7CA9
SCHEMBL16055171 0.83 MEN1 (0.51) CA12CA1CA2CA7CA9
SCHEMBL7933020 0.83 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL20247403 0.81 ESR1 (0.47) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL28568316 0.80 CYP1A2 (0.70) CA12CA1CA2CA7CA9
SCHEMBL16055776 0.80 CA12 (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed