SCHEMBL7930616

SCHEMBL7930616

CCNc1c(F)c(F)c2c(c1F)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.41
CSNK2A2 P19784 4/20 0.39
CSNK2B P67870 4/20 0.39
CSNK2A1 P68400 4/20 0.39
CSNK2A3 Q8NEV1 4/20 0.39
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
MAPK1 P28482 5/20 0.39
USP2 O75604 5/20 0.39
TP53 P04637 4/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
RECQL P46063 4/20 0.39
CYP3A4 P08684 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
BLM P54132 3/20 0.39
HIF1A Q16665 3/20 0.39
LMNA P02545 3/20 0.39
ALOX15 P16050 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933097 0.84 CYP19A1 (0.47) CYP19A1CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL7930645 0.82 CYP19A1 (0.44) CYP19A1CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL497324 0.78 CSNK2A2 (0.54) CYP19A1CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL7921158 0.77 CLCN2 (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL7933255 0.77 CYP19A1 (0.46) CYP19A1CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL11806000 0.75 CYP19A1 (0.62) CYP19A1CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL7921289 0.73 CSNK2A2 (0.39) CYP19A1CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL7929945 0.73 CLCN2 (0.40) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL7929777 0.73 CXCR2 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL7927120 0.72 CSNK2A2 (0.54) CYP19A1CSNK2A2CSNK2BCSNK2A1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed