SCHEMBL7933097

SCHEMBL7933097

CCCCNc1c(F)c(F)c2c(c1F)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.47
FTO Q9C0B1 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.38
MEN1 O00255 3/20 0.38
USP2 O75604 3/20 0.38
LMNA P02545 3/20 0.38
MAPK1 P28482 3/20 0.38
RECQL P46063 3/20 0.38
KMT2A Q03164 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
TP53 P04637 3/20 0.38
BLM P54132 2/20 0.38
HTT P42858 2/20 0.38
CSNK2A2 P19784 2/20 0.38
CSNK2B P67870 2/20 0.38
CSNK2A1 P68400 2/20 0.38
CSNK2A3 Q8NEV1 2/20 0.38
CYP3A4 P08684 2/20 0.38
HIF1A Q16665 2/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930645 0.94 CYP19A1 (0.44) CYP19A1FTOSMN1; SMN2MEN1USP2
SCHEMBL7933255 0.90 CYP19A1 (0.46) CYP19A1FTOSMN1; SMN2MEN1USP2
SCHEMBL7930616 0.84 CYP19A1 (0.41) CYP19A1FTOSMN1; SMN2MEN1USP2
SCHEMBL7930584 0.83 HDAC1 (0.40) CYP19A1SMN1; SMN2MEN1USP2LMNA
SCHEMBL8737131 0.82 ALDH1A1 (0.52) SMN1; SMN2MEN1USP2LMNAMAPK1
SCHEMBL7930620 0.79 HDAC3 (0.45) CYP19A1SMN1; SMN2MEN1LMNAMAPK1
SCHEMBL17732422 0.78 CYP19A1 (0.73) CYP19A1FTOSMN1; SMN2MEN1USP2
SCHEMBL8393295 0.78 SOAT1 (0.38) CYP19A1SMN1; SMN2
SCHEMBL10718098 0.77 CYP19A1 (0.44) CYP19A1FTOSMN1; SMN2MEN1USP2
SCHEMBL7928244 0.77 CYP19A1 (0.35) CYP19A1SMN1; SMN2MEN1USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed