SCHEMBL7930639

SCHEMBL7930639

CCCCOC(=O)c1ccc(Nc2c(F)c(F)c3c(c2F)C(=O)c2c(O)ccc(O)c2C3=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.50
RECQL P46063 1/20 0.50
ESR1 P03372 3/20 0.49
LMNA P02545 3/20 0.49
CYP1A2 P05177 3/20 0.49
TSHR P16473 2/20 0.49
CYP2C19 P33261 2/20 0.49
MAPK1 P28482 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP2D6 P10635 1/20 0.49
NR1H2 P55055 1/20 0.49
RNASEL Q05823 1/20 0.49
STS P08842 7/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
CASP1 P29466 1/20 0.46
MAPT P10636 3/20 0.46
PKM P14618 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921400 0.96 HPGD (0.52) HPGDRECQLESR1LMNACYP1A2
SCHEMBL7927180 0.89 MAPT (0.53) HPGDRECQLESR1CYP1A2TSHR
SCHEMBL7930660 0.88 STS (0.47) HPGDRECQLESR1LMNACYP1A2
SCHEMBL7921281 0.88 SMN1; SMN2 (0.52) HPGDESR1LMNACYP1A2CYP2C19
SCHEMBL7929778 0.85 MAPT (0.51) HPGDRECQLESR1LMNACYP1A2
SCHEMBL7921343 0.84 SMN1; SMN2 (0.47) HPGDESR1LMNACYP1A2CYP2C19
SCHEMBL7933212 0.83 SMN1; SMN2 (0.54) HPGDESR1LMNACYP1A2TSHR
SCHEMBL7929952 0.82 MAPT (0.49) HPGDRECQLTSHRSMN1; SMN2STS
SCHEMBL7921187 0.81 MAPT (0.48) HPGDRECQLTSHRSMN1; SMN2STS
SCHEMBL7928395 0.79 HPGD (0.51) HPGDRECQLESR1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed