SCHEMBL7930660

SCHEMBL7930660

CCCCCCCCOc1c(F)c2c(c(F)c1Nc1ccc(C(=O)OCCCC)cc1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 7/20 0.47
HPGD P15428 2/20 0.45
RECQL P46063 1/20 0.45
MAPT P10636 5/20 0.44
PKM P14618 1/20 0.44
TP53 P04637 1/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
ALDH1A1 P00352 1/20 0.44
ESR1 P03372 2/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
CYP2C19 P33261 1/20 0.44
NR1H2 P55055 1/20 0.44
RNASEL Q05823 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929952 0.94 MAPT (0.49) STSHPGDRECQLMAPTTP53
SCHEMBL7929778 0.92 MAPT (0.51) HPGDRECQLMAPTPKMTP53
SCHEMBL7921400 0.90 HPGD (0.52) STSHPGDRECQLMAPTPKM
SCHEMBL7930880 0.89 SMN1; SMN2 (0.47) STSHPGDMAPTTP53RAB9A
SCHEMBL7930639 0.88 HPGD (0.50) STSHPGDRECQLMAPTPKM
SCHEMBL7921187 0.88 MAPT (0.48) STSHPGDRECQLMAPTTP53
SCHEMBL7928461 0.86 STS (0.46) STSHPGDRECQLMAPTPKM
SCHEMBL7930631 0.83 SMN1; SMN2 (0.49) HPGDMAPTPKMTP53RAB9A
SCHEMBL7930657 0.82 ADAMTS5 (0.43) MAPTRAB9ANPC1ALDH1A1LMNA
SCHEMBL7933074 0.82 TBXA2R (0.38) HPGDRAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed