SCHEMBL7930727

SCHEMBL7930727

C[Si]1(C)c2cccc3c2C(c2ccccc2-3)[Ti](OC(=O)c2ccccc2)(OC(=O)c2ccccc2)C2c3ccccc3-c3cccc1c32

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.34
POLB P06746 1/20 0.33
F2 P00734 2/20 0.33
LMNA P02545 2/20 0.33
TP53 P04637 1/20 0.32
KMT2A Q03164 4/20 0.32
MEN1 O00255 2/20 0.32
GAA P10253 1/20 0.32
SLC6A3 Q01959 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
SLC6A2 P23975 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
ATM Q13315 1/20 0.31
HTR3E A5X5Y0 1/20 0.31
HTR3B O95264 1/20 0.31
CHRNA7 P36544 1/20 0.31
HTR3A P46098 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919524 0.91 SLC6A4 (0.33) TSHRPOLBKMT2AMEN1GAA
SCHEMBL7927598 0.86 POLB (0.42) POLBKMT2A
SCHEMBL7924640 0.82 POLB (0.33) TSHRPOLB
SCHEMBL7919525 0.82 ALDH1A1 (0.38) POLBLMNAKMT2AMEN1GAA
SCHEMBL7927567 0.82 KCNN4 (0.38) POLBKMT2AMEN1ATM
SCHEMBL7927133 0.81 POLB (0.33) POLB
SCHEMBL7928728 0.81 POLB (0.33) POLB
SCHEMBL7928446 0.81 POLB (0.35) POLB
SCHEMBL7928586 0.81 HTT (0.39) TSHRF2LMNATP53KMT2A
SCHEMBL7924685 0.81 SRD5A2 (0.35) TSHRF2LMNATP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed