Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094539 | 0.89 | ALDH1A1 (0.49) | GAAALDH1A1L3MBTL1GBA1POLB | |
| SCHEMBL16094744 | 0.85 | GAA (0.39) | GAAALDH1A1L3MBTL1SUMO3SUMO2 | |
| SCHEMBL16094971 | 0.85 | GAA (0.46) | GAAALDH1A1L3MBTL1GBA1POLB | |
| Hydrochloric Acid SCHEMBL17494524 | 0.84 | GAA (0.45) | GAAALDH1A1L3MBTL1GBA1POLB | |
| Hydrochloric Acid SCHEMBL17494541 | 0.84 | GAA (0.38) | GAAALDH1A1L3MBTL1SUMO3SUMO2 | |
| SCHEMBL3237315 | 0.83 | GAA (0.53) | GAAALDH1A1GBA1POLBKMT2A | |
| SCHEMBL16105004 | 0.78 | ALDH1A1 (0.54) | GAAALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL20164561 | 0.77 | CYP1A2 (0.44) | GAAALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL20164777 | 0.75 | SLC29A1 (0.53) | GAAALDH1A1GBA1POLBKMT2A | |
| SCHEMBL7678942 | 0.74 | KMT2A (0.39) | GAAALDH1A1L3MBTL1SUMO3SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |