Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 17/20 | 0.72 |
| ▸ | MMP3 | P08254 | 17/20 | 0.72 |
| ▸ | MMP7 | P09237 | 15/20 | 0.72 |
| ▸ | MMP1 | P03956 | 14/20 | 0.72 |
| ▸ | MMP8 | P22894 | 2/20 | 0.70 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.70 |
| ▸ | MMP9 | P14780 | 1/20 | 0.70 |
| ▸ | MMP12 | P39900 | 1/20 | 0.70 |
| ▸ | MMP13 | P45452 | 1/20 | 0.70 |
| ▸ | MMP14 | P50281 | 1/20 | 0.70 |
| ▸ | FCER2 | P06734 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805358 | 1.00 | MMP2 (0.72) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL6808734 | 1.00 | MMP2 (0.72) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4431907 | 0.90 | MMP2 (0.78) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4425335 | 0.90 | MMP2 (0.78) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4418755 | 0.89 | MMP2 (0.74) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4421723 | 0.88 | MMP2 (0.78) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4428170 | 0.88 | MMP2 (0.81) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4431974 | 0.86 | MMP2 (0.78) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4424468 | 0.84 | MMP2 (0.86) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL4423322 | 0.84 | MMP2 (0.75) | MMP2MMP3MMP7MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306881-B1 | ENZYME INHIBITORS ADMINISTERED TO MAMMALS AS ANTIINFLAMMATORY AGENTS | BRITISH BIOTECH PHARMACEUTICALS (GB) | 2001-10-23 | — | — | US | disclosed |