⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21259965 | 1.00 | — | — | |
| SCHEMBL23378932 | 1.00 | — | — | |
| SCHEMBL10060826 | 1.00 | — | — | |
| SCHEMBL13985991 | 0.71 | — | — | |
| SCHEMBL10057896 | 0.71 | DPP4 (0.42) | — | |
| SCHEMBL26167432 | 0.71 | DPP4 (0.45) | — | |
| SCHEMBL13818824 | 0.67 | DPP4 (0.39) | — | |
| SCHEMBL12969101 | 0.67 | — | — | |
| SCHEMBL15780006 | 0.67 | — | — | |
| SCHEMBL14899080 | 0.67 | DPP4 (0.78) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
| EP-2505579-B1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | ASTRAZENECA AB (SE) | 2014-11-05 | — | — | EP | disclosed |
| EP-2792672-A2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | AstraZeneca AB (SE) | 2014-10-22 | — | — | EP | disclosed |
| EP-2505578-B1 | Methods and Compounds for Producing Dipeptidyl Peptidase IV Inhibitors and Intermediates thereof | ASTRAZENECA AB (SE) | 2014-09-24 | — | — | EP | disclosed |
| EP-2517706-B1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | ASTRAZENECA AB (SE) | 2014-06-25 | — | — | EP | disclosed |
| US-20130137852-A1 | NOVEL COMPOUNDS AS DPP-IV INHIBITORS AND PROCESS FOR PREPARATION THEREOF | Cadila Corporate Campus (IN) | 2013-05-30 | — | — | US | disclosed |
| US-20130012723-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2505579-A2 | Methods and compounds for producing dipeptidyl peptidase iv inhibitors and intermediates thereof | Bristol-Myers Squibb Company (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011098985-A1 | METHOD FOR PREPARING ADAMANTYL COMPOUNDS | FINORGA (FR) | 2011-08-18 | — | — | WO | disclosed |
| WO-2010032129-A1 | METHOD FOR PRODUCING ADAMANTYL COMPOUNDS | FINORGA (FR) | 2010-03-25 | — | — | WO | disclosed |
| WO-2004052850-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |