Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922173 | 0.83 | KDM4E (0.35) | TBXAS1MEN1KMT2ATBXA2RPTGFR | |
| SCHEMBL7928601 | 0.74 | PTGER3 (0.60) | MEN1MAPTKMT2ATBXA2RPTGFR | |
| SCHEMBL7928606 | 0.74 | PTGER3 (0.60) | MEN1MAPTKMT2ATBXA2RPTGFR | |
| SCHEMBL7814525 | 0.73 | PTGER3 (0.59) | MEN1MAPTKMT2ATBXA2RPTGFR | |
| SCHEMBL7814518 | 0.73 | PTGER3 (0.59) | MEN1MAPTKMT2ATBXA2RPTGFR | |
| SCHEMBL9333725 | 0.73 | KDM4E (0.51) | MEN1MAPTKMT2ARAB9AHPGD | |
| SCHEMBL11335306 | 0.73 | GRIK1 (0.59) | TBXAS1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL321287 | 0.73 | GRIK1 (0.59) | TBXAS1MEN1MAPTKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL27356431 | 0.71 | GRIK1 (0.58) | TBXAS1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL7931389 | 0.71 | MAPT (0.46) | MEN1MAPTKMT2ATBXA2RPTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242493-B1 | PROSTAGLANDIN INHIBITORS; ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-06-05 | — | — | US | disclosed |