Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931394 | 0.83 | TBXAS1 (0.41) | MEN1KMT2AGRIK1TBXA2RPTGFR | |
| SCHEMBL7955217 | 0.79 | EPHX2 (0.41) | KDM4EKMT2ATBXAS1PPARGEPHX2 | |
| SCHEMBL9333725 | 0.75 | KDM4E (0.51) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7817711 | 0.73 | PTGER3 (0.56) | KDM4EALDH1A1TBXA2RPTGFRPTGER3 | |
| SCHEMBL7817709 | 0.73 | PTGER3 (0.56) | KDM4EALDH1A1TBXA2RPTGFRPTGER3 | |
| SCHEMBL11335306 | 0.72 | GRIK1 (0.59) | MEN1ALDH1A1KMT2AGRIK1TBXAS1 | |
| SCHEMBL321287 | 0.72 | GRIK1 (0.59) | MEN1ALDH1A1KMT2AGRIK1TBXAS1 | |
| SCHEMBL3080648 | 0.71 | ERN1 (0.52) | KDM4EALDH1A1TBXA2RPTGFRPTGER3 | |
| Hydrochloric Acid SCHEMBL27356431 | 0.70 | GRIK1 (0.58) | MEN1ALDH1A1KMT2AGRIK1TBXAS1 | |
| SCHEMBL11333114 | 0.70 | KMT2A (0.50) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242493-B1 | PROSTAGLANDIN INHIBITORS; ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-06-05 | — | — | US | disclosed |