Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931412 | 1.00 | TDP1 (0.74) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL17682026 | 0.88 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL8419623 | 0.88 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL8419626 | 0.88 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL3263647 | 0.88 | TDP1 (0.78) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL21323932 | 0.88 | TDP1 (0.78) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL490282 | 0.88 | TDP1 (0.78) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL3262244 | 0.88 | TDP1 (0.78) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL490281 | 0.88 | TDP1 (0.78) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL19244175 | 0.86 | TDP1 (0.76) | TDP1TSHRALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194627-B1 | REACTING HALOAROMATIC COMPOUND WITH OLEFIN IN PRESENCE OF PALLADIUM COMPOUND AS CATALYST | AVENTIS RESEARCH & TECHNOLOGY GMBH & CO. KG (DE) | 2001-02-27 | — | — | US | disclosed |
| US-5698755-A | Process for preparing aromatic olefins using palladacycle catalysis | HOECHST AG (DE) | 1997-12-16 | — | — | US | disclosed |