SCHEMBL490281

SCHEMBL490281

CCCCC(CC)COC(=O)/C=C/c1ccc(O)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.78
CA12 O43570 5/20 0.59
CA7 P43166 5/20 0.59
CA9 Q16790 5/20 0.59
CA14 Q9ULX7 5/20 0.59
CA2 P00918 4/20 0.59
CA1 P00915 4/20 0.59
TSHR P16473 2/20 0.55
CYP3A4 P08684 2/20 0.51
ALDH1A1 P00352 1/20 0.51
LMNA P02545 2/20 0.50
AKR1B10 O60218 3/20 0.49
AKR1B1 P15121 3/20 0.49
CA4 P22748 2/20 0.49
CA6 P23280 2/20 0.49
CA5A P35218 2/20 0.49
CA5B Q9Y2D0 2/20 0.49
MET P08581 1/20 0.49
TYR P14679 1/20 0.49
ESR1 P03372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490282 1.00 TDP1 (0.78) TDP1CA12CA7CA9CA14
SCHEMBL3263647 0.90 TDP1 (0.78) TDP1CA12CA7CA9CA14
SCHEMBL21323932 0.90 TDP1 (0.78) TDP1CA12CA7CA9CA14
SCHEMBL3262244 0.90 TDP1 (0.78) TDP1CA12CA7CA9CA14
SCHEMBL19244175 0.89 TDP1 (0.76) TDP1CA12CA7CA9CA14
SCHEMBL19244383 0.89 TDP1 (0.76) TDP1CA12CA7CA9CA14
SCHEMBL9453997 0.89 TDP1 (0.76) TDP1CA12CA7CA9CA14
SCHEMBL12104057 0.89 TDP1 (0.76) TDP1CA12CA7CA9CA14
SCHEMBL19244230 0.89 TDP1 (0.76) TDP1CA12CA7CA9CA14
SCHEMBL19244304 0.89 TDP1 (0.76) TDP1CA12CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9176613-A None JP disclosed
US-20230210755-A1 FUNCTIONAL SKIN COATING POLYMER THE JOHNS HOPKINS UNIVERSITY 2023-07-06 US disclosed
WO-2023080405-A1 PHOTOALIGNMENT COMPOUND, MANUFACTURING METHOD THEREFOR, LIQUID CRYSTAL PHOTOALIGNMENT AGENT USING SAME, AND RETARDATION FILM COMPRISING SAME 주식회사 클랩 2023-05-11 WO disclosed
WO-2023080405-A1 PHOTOALIGNMENT COMPOUND, MANUFACTURING METHOD THEREFOR, LIQUID CRYSTAL PHOTOALIGNMENT AGENT USING SAME, AND RETARDATION FILM COMPRISING SAME 주식회사 클랩 2023-05-11 WO disclosed
WO-2021242976-A1 FUNCTIONAL SKIN COATING POLYMER THE JOHNS HOPKINS UNIVERSITY (US) 2021-12-02 WO disclosed
EP-3166586-B1 ANHYDROUS OIL BASED ON DELIVERY PARTICLES CONTAINING A BENEFIT AGENT OREAL (FR) 2020-04-15 EP disclosed
EP-3546025-A2 USE OF OLEOGELS IN UV ABSORBER COMPOSITIONS BASF SE (DE) 2019-10-02 EP disclosed
US-10314778-B2 Anhydrous oil based on particles encapsulating a beneficial agent L'OREAL (FR) 2019-06-11 US disclosed
US-20170209361-A1 ANHYDROUS OIL BASED ON PARTICLES ENCAPSULATING A BENEFICIAL AGENT L'OREAL (FR) 2017-07-27 US disclosed
EP-2931715-B1 3-HYDROXY-4-OXO-4H-PYRANE OR 3-HYDROXY-4-OXO-1,4-DIHYDRO-PYRIDINE DERIVATIVES AS PROTEIN-ADHESIVE ACTIVE AGENTS MERCK PATENT GMBH (DE) 2016-12-21 EP disclosed
EP-2049075-A2 USE OF ASCORBIC ACID DERIVATIVES FOR THE FUNCTIONALIZATION OF MATRICES Merck Patent GmbH (DE) 2009-04-22 EP disclosed
US-20090098076-A1 Method For the Production of a Keratin-Binding Effector Molecule BASF SE (DE) 2009-04-16 US disclosed
US-20080171004-A1 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives MERCK PATENT GMBH (DE) 2008-07-17 US disclosed
US-20080152603-A1 Antioxidants SUSONITY Commercial GmbH (DE) 2008-06-26 US disclosed
WO-2008017346-A2 USE OF ASCORBIC ACID DERIVATIVES FOR THE FUNCTIONALIZATION OF MATRICES MERCK PATENT GMBH (DE) 2008-02-14 WO disclosed
EP-0882447-B1 SOLUBLE COSMETICS SHISEIDO CO LTD (JP) 2006-04-12 EP disclosed
US-6350459-B1 COMPOSITION CONTAINING ACRYLATE-METHACRYLATE ALKYL COPOLYMER AND HYDROXYALKYLATED CYCLODEXTRIN, EXHIBITING LONG TERM STABILITY OVER TIME IN SOLUBLE STATE, IMPROVED FEELING IN USE, SUPERIOR CLARITY SHISEIDO COMPANY, LTD. (JP) 2002-02-26 US disclosed
EP-0882447-A1 SOLUBLE COSMETICS SHISEIDO COMPANY LIMITED (JP) 1998-12-09 EP disclosed
US-5843410-A Polymeric ultraviolet screening agent and process for the preparation thereof LG CHEMICAL LTD. (KR) 1998-12-01 US disclosed
JP-H09176613-A HIGH-MOLECULAR ULTRAVIOLET-SCREENING AGENT AND ITS PRODUCTION LG CHEM LTD 1997-07-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210755-A1 FUNCTIONAL SKIN COATING POLYMER CUTA, PUF60, SUN2 TDP1 2559/4885CA12 3818/4885CA7 2782/4885
US-20080152603-A1 Antioxidants GPX4, GPX1, CAT TDP1 1049/4885CA12 3215/4885CA7 1952/4885
US-20080171004-A1 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives HPD, HAAO, UGT1A6 TDP1 2793/4885CA12 2109/4885CA7 589/4885
US-10314778-B2 Anhydrous oil based on particles encapsulating a beneficial agent KRT18, DSG1, EPCAM TDP1 3516/4885CA12 127/4885CA7 679/4885
US-20170209361-A1 ANHYDROUS OIL BASED ON PARTICLES ENCAPSULATING A BENEFICIAL AGENT KRT18, DSG1, EPCAM TDP1 3516/4885CA12 127/4885CA7 679/4885
US-20090098076-A1 Method For the Production of a Keratin-Binding Effector Molecule KRT18, KRTCAP2, CUTA TDP1 4613/4885CA12 1122/4885CA7 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.