Dectaflur

Dectaflur

SCHEMBL7931664

CCCCCCCC/C=C\CCCCCCCCN.NCCNCCNCCN

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 2/20 0.57
DNM1 Q05193 8/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
EPHX1 P07099 1/20 0.52
FAAH O00519 2/20 0.52
TRPV1 Q8NER1 1/20 0.52
PPARA Q07869 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dectaflur SCHEMBL8957313 0.98 SLC6A5 (0.58) SLC6A5DNM1MEN1KMT2AALDH1A1
SCHEMBL10939057 0.92 PPARA (0.53) SLC6A5MEN1KMT2AALDH1A1TSHR
SCHEMBL527624 0.92 PPARA (0.53) SLC6A5MEN1KMT2AALDH1A1TSHR
SCHEMBL8625697 0.92 SLC6A5 (0.61) SLC6A5DNM1MEN1KMT2AALDH1A1
SCHEMBL448390 0.92 SLC6A5 (0.61) SLC6A5DNM1MEN1KMT2AALDH1A1
SCHEMBL7574261 0.92 PPARA (0.53) SLC6A5MEN1KMT2AALDH1A1TSHR
SCHEMBL7574269 0.92 PPARA (0.53) SLC6A5MEN1KMT2AALDH1A1TSHR
SCHEMBL448392 0.92 SLC6A5 (0.61) SLC6A5DNM1MEN1KMT2AALDH1A1
SCHEMBL10519278 0.92 PPARA (0.53) SLC6A5MEN1KMT2AALDH1A1TSHR
SCHEMBL443552 0.92 SLC6A5 (0.61) SLC6A5DNM1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1134251-A1 Primer composition Kaneka Corporation (JP) 2001-09-19 EP disclosed