SCHEMBL7931783

SCHEMBL7931783

CC(C=O)CC(C)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
SIGMAR1 Q99720 4/20 0.45
SLC6A2 P23975 2/20 0.45
MAOA P21397 1/20 0.45
SLC6A4 P31645 1/20 0.45
SLC6A3 Q01959 1/20 0.45
CYP2A6 P11509 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
EPHX1 P07099 1/20 0.44
SLC18A2 Q05940 1/20 0.42
CYP2D6 P10635 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TRPA1 O75762 1/20 0.41
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29249332 0.85 TSHR (0.49) MEN1KMT2ATP53TSHREPHX1
SCHEMBL286217 0.84 TP53 (0.60) TAAR1MEN1KMT2ASIGMAR1SLC6A2
SCHEMBL97559 0.84 TP53 (0.60) TAAR1MEN1KMT2ASIGMAR1SLC6A2
SCHEMBL3484487 0.84 TP53 (0.60) TAAR1MEN1KMT2ASIGMAR1SLC6A2
SCHEMBL7599594 0.81 TAAR1 (0.47) TAAR1MEN1KMT2ASIGMAR1SLC6A2
SCHEMBL13490179 0.81 EPHX1 (0.55) TAAR1MEN1KMT2ASIGMAR1SLC6A2
SCHEMBL15866011 0.81 TSHR (0.46) TAAR1MEN1KMT2ASLC6A2SLC6A3
SCHEMBL8072287 0.81 SIGMAR1 (0.58) TAAR1MEN1KMT2ASIGMAR1SLC6A2
SCHEMBL7394097 0.77 TAAR1 (0.54) TAAR1MEN1KMT2ASIGMAR1SLC6A2
SCHEMBL11461422 0.77 TP53 (0.58) TAAR1MEN1KMT2ASIGMAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310033-B1 2,4-DIMETHYL-5-PHENYLPENTANAL; PERFUMES BUSH BOAKE ALLEN INC. 2001-10-30 US claimed
US-6310033-B1 2,4-DIMETHYL-5-PHENYLPENTANAL; PERFUMES BUSH BOAKE ALLEN INC. 2001-10-30 US disclosed