Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722771 | 0.90 | NR5A1 (0.48) | NR5A1RARBRARALTA4HALDH2 | |
| SCHEMBL5722664 | 0.84 | RARB (0.45) | NR5A1RARBRARALTA4HTP53 | |
| SCHEMBL7561237 | 0.82 | NR5A1 (0.47) | NR5A1RARBRARALTA4HALDH2 | |
| SCHEMBL25797784 | 0.82 | NR5A1 (0.58) | NR5A1RARBRARALTA4HTP53 | |
| SCHEMBL7920103 | 0.80 | RARB (0.46) | RARBRARATP53TSHRPLA2G4B | |
| SCHEMBL25797783 | 0.78 | NR5A1 (0.57) | NR5A1RARBRARALTA4HTP53 | |
| SCHEMBL8774093 | 0.78 | NR5A1 (0.57) | NR5A1RARBRARALTA4HTP53 | |
| SCHEMBL9663860 | 0.78 | NR5A1 (0.57) | NR5A1RARBRARALTA4HTP53 | |
| SCHEMBL5722644 | 0.77 | NPC1 (0.40) | NR5A1RARBALDH2TP53TSHR | |
| SCHEMBL28576384 | 0.76 | NR5A1 (0.68) | NR5A1RARBLTA4HALDH2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946474-B1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-6159561-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |