Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722771 | 0.86 | NR5A1 (0.48) | NPC1RAB9AHSD17B10RARBNR5A1 | |
| SCHEMBL5722670 | 0.82 | ERN1 (0.37) | PTPN11 | |
| SCHEMBL5722784 | 0.81 | NR5A1 (0.39) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9198614 | 0.80 | MGLL (0.46) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7109864 | 0.80 | MGLL (0.46) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7849805 | 0.78 | NR5A1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7839694 | 0.78 | NR5A1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL5722894 | 0.78 | NPC1 (0.33) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9426785 | 0.74 | RAB9A (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6534793 | 0.74 | NR5A1 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028944-B1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2006-01-11 | — | — | EP | disclosed |
| US-6491989-B1 | 6,7-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES, 1,1,6,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES, 1,6,7-TRIFLUORONAPHTHALENE DERIVATIVES AND 2,3-DIFLUORONAPHTHALENE DERIVATIVES | AVENTIS RESEACH & TECHNOLOGIES GMBH & CO. KG (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1028944-A1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999023074-A1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-05-14 | — | — | WO | disclosed |