Sulfur Dioxide

Sulfur Dioxide

SCHEMBL7932036

O=S=O.Oc1ccc2cc(Br)ccc2c1Br

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.57
ESR1 P03372 2/20 0.54
ESR2 Q92731 2/20 0.54
POLB P06746 2/20 0.50
HSD17B1 P14061 1/20 0.50
HSD17B2 P37059 1/20 0.50
MAPT P10636 4/20 0.45
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
NCEH1 Q6PIU2 1/20 0.45
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 2/20 0.42
HPGD P15428 2/20 0.41
CES2 O00748 1/20 0.41
GALR3 O60755 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CASP1 P29466 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50832 0.92 ESR1 (0.61) ERN1ESR1ESR2POLBHSD17B1
Sulfurous Acid SCHEMBL8518785 0.87 ERN1 (0.56) ERN1ESR1ESR2POLBHSD17B1
SCHEMBL7756493 0.84 POLB (0.75) ERN1ESR1ESR2POLBHSD17B1
SCHEMBL29833499 0.78 POLB (0.59) ERN1ESR1ESR2POLBHSD17B1
SCHEMBL5752732 0.78 POLB (0.59) ERN1ESR1ESR2POLBHSD17B1
SCHEMBL6356696 0.76 ERN1 (0.59) ERN1ESR1ESR2POLBMAPT
SCHEMBL9623620 0.76 ESR1 (0.72) ERN1ESR1ESR2POLBHSD17B1
SCHEMBL29365143 0.76 ERN1 (0.59) ERN1ESR1ESR2POLBHSD17B1
SCHEMBL993774 0.76 ERN1 (0.59) ERN1ESR1ESR2POLBHSD17B1
SCHEMBL30570998 0.76 ESR1 (0.72) ERN1ESR1ESR2POLBHSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934240-B1 PRODUCTION OF 6-BROMO-2-NAPHTHOL AND DERIVATIVES ALBEMARLE CORP (US) 2001-01-10 EP disclosed
EP-0934240-A1 PRODUCTION OF 6-BROMO-2-NAPHTHOL AND DERIVATIVES ALBEMARLE CORPORATION (US) 1999-08-11 EP disclosed
WO-1998011041-A1 PRODUCTION OF 6-BROMO-2-NAPHTHOL AND DERIVATIVES ALBEMARLE CORPORATION (US) 1998-03-19 WO disclosed