SCHEMBL993774

SCHEMBL993774

Oc1ccc2cc(Br)ccc2c1-c1c(O)ccc2cc(Br)ccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.59
MAPT P10636 5/20 0.50
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
ALOX15 P16050 2/20 0.48
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 5/20 0.46
CYP1A2 P05177 3/20 0.44
CYP2C9 P11712 3/20 0.44
CYP2C19 P33261 3/20 0.44
HSD17B1 P14061 3/20 0.44
HSD17B2 P37059 3/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2B6 P20813 2/20 0.44
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
CYP2A6 P11509 1/20 0.43
HPGD P15428 2/20 0.42
CES2 O00748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365143 1.00 ERN1 (0.59) ERN1MAPTMEN1KMT2AALOX15
SCHEMBL26345927 0.94 ERN1 (0.54) ERN1MAPTMEN1KMT2AALOX15
SCHEMBL26205109 0.92 ERN1 (0.56) ERN1MAPTMEN1KMT2AALOX15
SCHEMBL8653093 0.91 POLB (0.53) ERN1MAPTMEN1KMT2ACYP1A2
SCHEMBL5620225 0.91 POLB (0.53) ERN1MAPTMEN1KMT2ACYP1A2
SCHEMBL24891578 0.88 ERN1 (0.53) ERN1MAPTMEN1KMT2AALOX15
SCHEMBL18529230 0.85 ESR1 (0.64) ERN1MAPTMEN1KMT2AKDM4E
SCHEMBL25953081 0.85 ERN1 (0.50) ERN1MAPTMEN1KMT2AALOX15
SCHEMBL12949860 0.85 ERN1 (0.46) ERN1MAPTMEN1KMT2AALOX15
SCHEMBL19712934 0.85 ERN1 (0.46) ERN1MAPTMEN1KMT2AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040785-A Metal organic framework composite material with circularly polarized room temperature phosphorescence characteristic and preparation method thereof 南京工业大学 2025-05-27 CN claimed
CN-118878923-A Modified calcium carbonate applied to flame-retardant polypropylene filling and preparation method thereof 江苏恒凌奇科技有限公司 2024-11-01 CN claimed
CN-113999089-B Method for synthesizing 6,6 '-dibromo-1, 1' -bi-2-naphthol by oxidative coupling of 6-bromo-2-naphthol 中唯炼焦技术国家工程研究中心有限责任公司 2024-05-14 CN claimed
CN-112920813-B Photo-thermal response chiral photosensitive liquid crystal dopant containing azobenzene binaphthyl 湘潭大学 2023-08-22 CN claimed
CN-111519275-B Sheath-core structure composite fiber and nonwoven fabric comprising same 天津工业大学 2022-07-08 CN claimed
CN-113999089-A Method for synthesizing 6,6 '-dibromo-1, 1' -bi-2-naphthol by oxidative coupling of 6-bromo-2-naphthol 中唯炼焦技术国家工程研究中心有限责任公司 2022-02-01 CN claimed
CN-112409136-A Method for preparing 6,6 ' -dibromo-1, 1 ' -binaphthyl-2, 2 ' -diphenol by efficient clean bromination 中唯炼焦技术国家工程研究中心有限责任公司 2021-02-26 CN claimed
US-8084611-B2 Process for preparing tetrahydroquinoline derivatives MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-12-27 US claimed
EP-2004622-B1 CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS MERCK PATENT GMBH (DE) 2011-12-14 EP claimed
US-7943061-B2 Chiral binaphthyl sulfates for use as liquid crystal materials MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-17 US claimed
US-20080281108-A1 Chiral Compounds MERCK PATENT GMBH (DE) 2008-11-13 US claimed
EP-1928854-A1 CHIRAL COMPOUNDS Merck Patent GmbH (DE) 2008-06-11 EP claimed
WO-2007124383-A2 1,1'-BINAPHTHYL-BASED INHIBITORS OF NAD+-DEPENDENT DEACETYLASE ACTIVITY AND SIR2-FAMILY MEMBERS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2007-11-01 WO claimed
WO-2007116922-A1 A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-10-18 WO claimed
WO-2007039105-A1 CHIRAL COMPOUNDS MERCK PATENT GMBH (DE) 2007-04-12 WO claimed
US-6384228-B2 EPIBATIDINE; ANALGESICS; ANIMAL EXTRACTS NIHON MEDI-PHYSICS CO., LTD. (JP) 2002-05-07 US claimed
US-6339159-B1 REACTING AN ALDEHYDE COMPOUND, AN AMINO COMPOUND AND HYDROGEN CYANATE IN THE PRESENCE OF A CHIRAL ZIRCONIUM CATALYST OBTAINED BY MIXING ZIRCONIUM ALKOXIDE WITH OPTICALLY ACTIVE BINAPHTHOL COMPOUND TO FORM ALPHA-AMINONITRILE JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2002-01-15 US claimed
EP-0764878-B1 Photothermographic elements comprising hydroxamic acid developers IMATION CORP (US) 2000-05-24 EP claimed
EP-0471498-B1 Optical resolution method KANKYO KAGAKU CENTER (JP) 1997-12-17 EP claimed
EP-0764878-A1 Photothermographic elements comprising hydroxamic acid developers Imation Corp. (US) 1997-03-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281108-A1 Chiral Compounds LAGE3, DDT, CUTA ERN1 3021/4885MAPT 2299/4885MEN1 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.