SCHEMBL7932055

SCHEMBL7932055

COc1nc(N)nc(Cl)c1OC(F)F

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
CCNA1 P78396 1/20 0.39
NPSR1 Q6W5P4 1/20 0.31
CRHR1 P34998 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26977761 0.87 CCNA2 (0.40) CCNA2CDK2CCNA1CRHR1
SCHEMBL7934006 0.83 DPP4 (0.31) NPSR1
SCHEMBL8874251 0.82 KDM4E (0.39) CCNA2CDK2CCNA1
SCHEMBL30559673 0.81 CCNA2 (0.46) CCNA2CDK2CCNA1NPSR1
SCHEMBL26977474 0.81 CCNA2 (0.46) CCNA2CDK2CCNA1NPSR1
SCHEMBL26977656 0.77 CCNA2 (0.33) CCNA2CDK2CCNA1
SCHEMBL7925343 0.77 LRRK2 (0.31)
SCHEMBL30559721 0.77 CCNA2 (0.33) CCNA2CDK2CCNA1
SCHEMBL8873470 0.75 CDK1 (0.42) CCNA2CDK2CCNA1
SCHEMBL8874055 0.75 RAB9A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446743-B1 Herbicidal sulfonylureas, process for their preparation and intermediates BASF AG (DE) 1995-08-02 EP claimed
US-6235904-B1 VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. BASF AKTIENGESELLSCHAFT (DE) 2001-05-22 US disclosed
US-5591694-A COMPOUND USED TO CONTROL UNDESIRABLE PLANT GROWTH BASF AKTIENGESELLSCHAFT (DE) 1997-01-07 US disclosed
US-5434124-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1995-07-18 US disclosed
US-5283332-A 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1994-02-01 US disclosed
US-5276007-A Herbicidal sulfonylureas BASF AKTIENGESELLSCHAFT (DE) 1994-01-04 US disclosed
US-5237063-A TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed