1,8-Naphthalic Anhydride

1,8-Naphthalic Anhydride

SCHEMBL7932111

O=C1CCC(=O)O1.O=C1OC(=O)c2cccc3cccc1c23

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 7/20 0.76
ALDH1A1 P00352 5/20 0.50
CES2 O00748 1/20 0.50
BCHE P06276 1/20 0.50
CES1 P23141 1/20 0.50
MCL1 Q07820 1/20 0.50
HSD17B10 Q99714 4/20 0.47
KDM4E B2RXH2 4/20 0.47
HPGD P15428 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
PARP1 P09874 1/20 0.45
ALOX15 P16050 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 2/20 0.44
PABPC1 P11940 2/20 0.44
CYP3A4 P08684 1/20 0.44
DNMT1 P26358 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,8-Naphthalic Anhydride SCHEMBL30415 0.87 TYMS (1.00) TYMSALDH1A1CES2BCHECES1
1,8-Naphthalic Anhydride SCHEMBL29351054 0.87 TYMS (1.00) TYMSALDH1A1CES2BCHECES1
1,8-Naphthalic Anhydride SCHEMBL6929962 0.85 TYMS (0.95) TYMSALDH1A1CES2BCHECES1
1,8-Naphthalic Anhydride SCHEMBL11692800 0.85 TYMS (0.95) TYMSALDH1A1CES2BCHECES1
1,8-Naphthalic Anhydride SCHEMBL10012400 0.83 TYMS (0.91) TYMSALDH1A1CES2BCHECES1
Phthalic Anhydride SCHEMBL8030359 0.81 TDP1 (0.70) TYMSALDH1A1CES1HSD17B10KDM4E
1,8-Naphthalic Anhydride SCHEMBL29143033 0.79 TYMS (0.83) TYMSALDH1A1CES2BCHECES1
1,8-Naphthalic Anhydride SCHEMBL21046340 0.79 TYMS (0.83) TYMSALDH1A1CES2BCHECES1
1,8-Naphthalic Anhydride SCHEMBL10012771 0.76 TYMS (0.76) TYMSALDH1A1CES2BCHECES1
Naphthalene SCHEMBL27718735 0.75 TSHR (0.61) TYMSMCL1HSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1071729-A1 HIGH TEMPERATURE RESISTANT COATING COMPOSITION AND METHOD OF USING THEREOF H.B. Fuller Company (US) 2001-01-31 EP disclosed
WO-1999046343-A1 HIGH TEMPERATURE RESISTANT COATING COMPOSITION AND METHOD OF USING THEREOF H.B. FULLER COMPANY (US) 1999-09-16 WO disclosed