SCHEMBL7932169

SCHEMBL7932169

O=C(O)c1cc([Na])cc(C(=O)OCCOCCO)c1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SERPINE1 P05121 2/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
ALDH1A1 P00352 2/20 0.30
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
HPGD P15428 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
HSD17B10 Q99714 1/20 0.30
PTGS2 P35354 1/20 0.30
KMT2A Q03164 1/20 0.30
PTK2B Q14289 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL7932171 0.91 CYP2D6 (0.34) ALDH1A1KDM4EHPGDCASP1CASP7
Di(Hydroxyethyl)Ether SCHEMBL11766502 0.89 CYP2D6 (0.33) ALDH1A1KDM4EHPGDCASP1CASP7
SCHEMBL483848 0.86 ALDH1A1 (0.38) SERPINE1ALDH1A1KDM4EGLAHPGD
SCHEMBL10491295 0.80 TSHR (0.41) LMNACYP1A2CYP2C9CYP2C19CA12
SCHEMBL28518303 0.77 CYP2D6 (0.31) ALDH1A1
1,3-Propanediol SCHEMBL27591428 0.77 CYP2D6 (0.36) CA2ALDH1A1KDM4EHPGDCASP1
1,3-Propanediol SCHEMBL27591480 0.77 CYP2D6 (0.36) CA2ALDH1A1KDM4EHPGDCASP1
SCHEMBL11766499 0.77
SCHEMBL63328 0.77 CYP2D6 (0.42) LMNACYP1A2CA12CA1CA2
SCHEMBL11581456 0.76 SERPINE1 (0.43) LMNACYP1A2CYP2C9CYP2C19SERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845012-B1 WATER-DISPERSIBLE COPOLYESTER-ETHER COMPOSITIONS EASTMAN CHEM CO (US) 2001-11-07 EP disclosed
EP-0845012-A1 WATER-DISPERSIBLE COPOLYESTER-ETHER COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-03 EP disclosed
US-5646237-A SULFO-SUBSTITUTED AROMATIC DICARBOXYLIC ACID MONOMER; WEAR AND BLOCKING RESISTANCE IN FIBER SIZING EASTMAN CHEMICAL COMPANY (US) 1997-07-08 US disclosed
WO-1997007154-A1 WATER-DISPERSIBLE COPOLYESTER-ETHER COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1997-02-27 WO disclosed
US-5571620-A SIZED FIBROUS ARTICLE EASTMAN CHEMICAL COMPANY (US) 1996-11-05 US disclosed