Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364009 | 0.86 | MME (0.52) | RAB9ANPC1HTTATMMME | |
| SCHEMBL28018732 | 0.82 | GRM5 (0.52) | RAB9ANPC1HTTATMMME | |
| SCHEMBL4344801 | 0.81 | NPC1 (0.44) | RAB9ANPC1HTTATMMME | |
| SCHEMBL19306197 | 0.80 | RAB9A (0.43) | RAB9ANPC1HTTATMMME | |
| SCHEMBL28018731 | 0.79 | MME (0.47) | RAB9ANPC1HTTATMMME | |
| SCHEMBL31509923 | 0.79 | CYP2A6 (0.41) | RAB9ANPC1KDM4EL3MBTL1KMT2A | |
| SCHEMBL7937049 | 0.79 | CYP2A6 (0.41) | RAB9ANPC1KDM4EL3MBTL1KMT2A | |
| SCHEMBL2558369 | 0.77 | NPC1 (0.41) | RAB9ANPC1HTTATMMME | |
| SCHEMBL17817792 | 0.77 | SMN1; SMN2 (0.44) | RAB9ANPC1HTTATMMME | |
| SCHEMBL2693858 | 0.76 | SMN1; SMN2 (0.43) | RAB9ANPC1HTTATMMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030967-A1 | 4-ARYLOXYQUINOLIN-2(1H)-ONES AS MTOR KINASE AND PI3 KINASE INHIBITORS, FOR USE AS ANTI-CANCER AGENTS | WYETH LLC (US) | 2010-03-18 | — | — | WO | disclosed |