Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | NT5E | P21589 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.69 |
| ▸ | DPP4 | P27487 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25756712 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL314542 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL259446 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL6725190 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL14131245 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL24146779 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL13461111 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL10040218 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL278293 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A | |
| SCHEMBL6934755 | 1.00 | ADORA3 (0.76) | ADORA3LMNANT5EHIF1AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232297-B1 | ADMINISTERING 4-AMINOPYRROLO(3,2-D)PYRIMIDINE DERIVATIVE AS ADENOSINE RECEPTOR ANTAGONIST | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2001-05-15 | — | — | US | disclosed |