Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932599 | 0.90 | CCR3 (0.71) | CCR3TACR1 | |
| SCHEMBL7938483 | 0.89 | GAA (0.76) | CCR3GAATACR1L3MBTL1ALDH1A1 | |
| SCHEMBL7925896 | 0.88 | CCR3 (0.69) | CCR3GAATACR1ALDH1A1 | |
| SCHEMBL7934635 | 0.87 | CCR3 (0.64) | CCR3GAATACR1L3MBTL1ALDH1A1 | |
| SCHEMBL7936431 | 0.86 | GAA (0.66) | CCR3GAATACR1L3MBTL1 | |
| SCHEMBL7934825 | 0.85 | GAA (0.64) | CCR3GAATACR1L3MBTL1TP53 | |
| SCHEMBL7932676 | 0.82 | CCR3 (0.59) | CCR3GAATACR1L3MBTL1ALDH1A1 | |
| SCHEMBL18840871 | 0.82 | CCR3 (1.00) | CCR3TP53 | |
| SCHEMBL7925931 | 0.82 | TACR1 (0.78) | CCR3TACR1 | |
| SCHEMBL18840945 | 0.81 | CCR3 (1.00) | CCR3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |