Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 12/20 | 0.69 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932599 | 0.89 | CCR3 (0.71) | CCR3TACR1SLC1A2MEN1KMT2A | |
| SCHEMBL7932765 | 0.88 | CCR3 (0.70) | CCR3TACR1GAAALDH1A1 | |
| SCHEMBL18840871 | 0.82 | CCR3 (1.00) | CCR3LMNA | |
| SCHEMBL7934635 | 0.78 | CCR3 (0.64) | CCR3TACR1GAAALDH1A1 | |
| SCHEMBL7932702 | 0.77 | MEN1 (0.70) | CCR3SLC1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7938483 | 0.77 | GAA (0.76) | CCR3TACR1GAAMEN1ALDH1A1 | |
| SCHEMBL18840846 | 0.77 | CCR3 (1.00) | CCR3TACR1 | |
| SCHEMBL18840945 | 0.77 | CCR3 (1.00) | CCR3TACR1 | |
| SCHEMBL7938462 | 0.76 | CCR3 (0.66) | CCR3TACR1 | |
| SCHEMBL7925817 | 0.76 | TACR1 (0.62) | CCR3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |