Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1082559 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Hydrochloric Acid SCHEMBL9566432 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL9561811 | 0.94 | — | — | |
| SCHEMBL21178 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL6514209 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL23209660 | 0.88 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL20608390 | 0.88 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Hydrochloric Acid SCHEMBL10425993 | 0.88 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL25187157 | 0.88 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL21625339 | 0.88 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6261687-B1 | BLEND CONTAINING CHELATED METAL OXIDE | RELIANCE ELECTRIC TECHNOLOGIES, LLC | 2001-07-17 | — | — | US | disclosed |
| US-6224979-B1 | INSULATING RESIN WITH CORONA RESISTANCE IN ELECTRICAL MOTORS, POLYMERIZATION MATERIAL AND A POLYCONDENSATION PRODUCT OF A PARTIALLY HYDROLYZED CHELATED METAL OXIDE PRECURSOR. | RELIANCE ELECTRIC TECHNOLOGIES, LLC | 2001-05-01 | — | — | US | disclosed |
| US-6159600-A | Oxygen plasma resistant polymer for electrical devices | RELIANCE ELECTRIC TECHNOLOGIES, LLC (US) | 2000-12-12 | — | — | US | disclosed |