SCHEMBL7933127

SCHEMBL7933127

CC(C)N(CCC#N)C(C)C.OP(O)OCl

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5063666 0.87 MEN1 (0.32) MEN1KMT2A
SCHEMBL25396096 0.82 KMT2A (0.34) MEN1KMT2A
SCHEMBL150064 0.82 MEN1 (0.43) MEN1KMT2A
SCHEMBL1524334 0.82 MEN1 (0.43) MEN1KMT2A
SCHEMBL9652607 0.80 MEN1 (0.44) MEN1KMT2A
SCHEMBL5063668 0.78 MEN1 (0.37) MEN1KMT2A
SCHEMBL27478061 0.71 CHRM2 (0.31)
SCHEMBL152625 0.71 TSHR (0.43) MEN1KMT2A
SCHEMBL1069687 0.70
SCHEMBL5146782 0.69 TSHR (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0819134-B1 COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES, METHOD FOR PREPARING SAME, AND SYNTHON USED THEREIN GENSET SA (FR) 2001-07-18 EP disclosed
EP-0819134-A1 COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES, METHOD FOR PREPARING SAME, AND SYNTHON USED THEREIN GENSET SA (FR) 1998-01-21 EP disclosed