SCHEMBL150064

SCHEMBL150064

CC(C)N(CCC#N)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TSHR P16473 3/20 0.40
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NLRP3 Q96P20 1/20 0.35
LCK P06239 1/20 0.34
MAPK1 P28482 2/20 0.33
CYP1A2 P05177 1/20 0.33
LOX P28300 1/20 0.30
LOXL3 P58215 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1524334 1.00 MEN1 (0.43) MEN1KMT2ATSHRALDH1A1TDP1
SCHEMBL9652607 0.93 MEN1 (0.44) MEN1KMT2ATSHRALDH1A1TDP1
SCHEMBL5063668 0.91 MEN1 (0.37) MEN1KMT2ATSHRALDH1A1TDP1
SCHEMBL25396096 0.87 KMT2A (0.34) MEN1KMT2ATSHRALDH1A1LCK
SCHEMBL152625 0.86 TSHR (0.43) MEN1KMT2ATSHRALDH1A1TDP1
SCHEMBL27497447 0.84 TSHR (0.42) MEN1KMT2ATSHRALDH1A1TDP1
SCHEMBL24726035 0.84 TSHR (0.37) MEN1KMT2ATSHR
SCHEMBL5063666 0.83 MEN1 (0.32) MEN1KMT2ATSHR
SCHEMBL27895185 0.82 TSHR (0.40) MEN1KMT2ATSHRALDH1A1TDP1
SCHEMBL7933127 0.82 MEN1 (0.35) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025119782-A1 METHOD FOR THE MANUFACTURE OF NEW AMINE EVONIK OPERATIONS GMBH (DE) 2025-06-12 WO claimed
EP-4298104-A1 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION Agilent Technologies, Inc. (US) 2024-01-03 EP claimed
WO-2022183081-A9 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION AGILENT TECHNOLOGIES, INC. (US) 2023-09-21 WO claimed
WO-2022183081-A1 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION AGILENT TECHNOLOGIES, INC. (US) 2022-09-01 WO claimed
US-20220275019-A1 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION AGILENT TECHNOLOGIES, INC. 2022-09-01 US claimed
CN-103370416-A Modified single-strand polynucleotide DAIICHI SANKYO CO LTD 2013-10-23 CN claimed
WO-2025119782-A1 METHOD FOR THE MANUFACTURE OF NEW AMINE EVONIK OPERATIONS GMBH (DE) 2025-06-12 WO disclosed
EP-4298104-A1 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION Agilent Technologies, Inc. (US) 2024-01-03 EP disclosed
WO-2022183081-A9 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION AGILENT TECHNOLOGIES, INC. (US) 2023-09-21 WO disclosed
WO-2022183081-A1 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION AGILENT TECHNOLOGIES, INC. (US) 2022-09-01 WO disclosed
US-20220275019-A1 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION AGILENT TECHNOLOGIES, INC. 2022-09-01 US disclosed
EP-3952917-A1 PROGRAMMABLE POLYMERIC DRUGS Sony Group Corporation (JP) 2022-02-16 EP disclosed
EP-3952916-A1 PROGRAMMABLE POLYMERIC DRUGS Sony Group Corporation (JP) 2022-02-16 EP disclosed
EP-0367040-B1 COMPOUNDS FOR THE TREATMENT OF URINARY INCONTINENCE Kabi Pharmacia AB (SE) 1993-04-21 EP disclosed
EP-0202758-B1 HYBRIDIZATION METHOD AND PROBES THEREFOR Zeneca Limited (GB) 1991-09-25 EP disclosed
WO-1991010671-A1 COMPOSITIONS AND METHODS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 1991-07-25 WO disclosed
EP-0367040-A1 Compounds for the treatment of urinary incontinence Kabi Pharmacia AB (SE) 1990-05-09 EP disclosed
EP-0305201-A2 Protected biotin derivatives ZENECA LIMITED (GB) 1989-03-01 EP disclosed
EP-0202758-A1 Hybridization method and probes therefor ZENECA LIMITED (GB) 1986-11-26 EP disclosed
US-4038210-A BETA-AMINO NITRILE CATALYSTS FOR POLYURETHANE PREPARATION UNION CARBIDE CORPORATION (US) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220275019-A1 HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION NSUN2, RNASEH1, RNMT MEN1 1215/4885KMT2A 625/4885TSHR 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.