Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932839 | 1.00 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL7926530 | 1.00 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL7933193 | 1.00 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL7932841 | 1.00 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8672064 | 0.82 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8675884 | 0.82 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8671073 | 0.82 | HTR1A (1.00) | HTR1A | |
| Hydrochloric Acid SCHEMBL7926404 | 0.81 | HTR1A (0.98) | HTR1A | |
| Hydrochloric Acid SCHEMBL7932964 | 0.81 | HTR1A (0.98) | HTR1A | |
| Hydrochloric Acid SCHEMBL7932960 | 0.81 | HTR1A (0.98) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331636-B1 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, DIABETES, HYPERTENSION, IMPOTENCY, APPETITE CONTROL | THE UPJOHN COMPANY | 2001-12-18 | — | — | US | disclosed |
| EP-0482084-B1 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-05-07 | — | — | EP | disclosed |
| US-5545755-A | USEFUL TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS, HYPERTENSION, DIABETES, SEXUAL IMPOTENCY AND TO CONTROL APPETITE | THE UPJOHN COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| US-5491236-A | NERVOUS SYTEM DISORDERS | THE UPJOHN COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| EP-0476016-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| WO-1990015047-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |