SCHEMBL7933247

SCHEMBL7933247

N#Cc1ccccc1Nc1c(F)c(F)c2c(c1F)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 5/20 0.43
GAA P10253 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
PDK1 Q15118 1/20 0.36
PDK2 Q15119 1/20 0.36
PDK3 Q15120 1/20 0.36
PDK4 Q16654 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
MAOA P21397 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
FLT1 P17948 1/20 0.35
FLT4 P35916 1/20 0.35
KDR P35968 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933039 0.95 CXCR2 (0.45) CXCR2GAAKDM4ELMNACA12
SCHEMBL21817074 0.86 USP8 (0.40) CXCR2GAAKDM4ELMNACA12
SCHEMBL29502777 0.86 USP8 (0.40) CXCR2GAAKDM4ELMNACA12
SCHEMBL7928265 0.80 TSHR (0.41) CXCR2GAACA12CA1CA2
SCHEMBL7921212 0.76 EGFR (0.49) GAAKDM4ELMNACA12CA1
SCHEMBL7928254 0.76 CXCR2 (0.45) CXCR2LMNAMEN1MAPTMAOA
SCHEMBL7930796 0.76 CXCR2 (0.44) CXCR2LMNACA12CA1CA2
SCHEMBL7930479 0.75 CYP3A4 (0.54) CXCR2GAAKDM4ELMNACA12
SCHEMBL7921433 0.73 MEN1 (0.45) CXCR2GAAKDM4ELMNACA12
SCHEMBL7921289 0.71 CSNK2A2 (0.39) GAAKDM4ELMNACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed