Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6917363 | 0.73 | HTR2A (0.31) | — | |
| SCHEMBL4624071 | 0.69 | TAAR1 (0.44) | TAAR1AOC3MAOAMAOBNISCH | |
| Hydrochloric Acid SCHEMBL9077192 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8041751 | 0.66 | TSHR (0.31) | — | |
| Hydrochloric Acid SCHEMBL7933384 | 0.65 | TAAR1 (0.40) | TAAR1AOC3MAOAMAOBNISCH | |
| Hydrochloric Acid SCHEMBL7169728 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL3680366 | 0.63 | — | — | |
| SCHEMBL9302592 | 0.62 | TYR (0.39) | TAAR1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7060706 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL647873 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791607-B1 | Substituted metallocene catalyst for the (co)polymerization of olefins | ENICHEM SPA (IT) | 2001-05-02 | — | — | EP | disclosed |
| US-5936051-A | FORMING POLYMERS OF HIGH MOLECULAR WEIGHT; CHEMICAL AND HEAT RESISTANCE; ALUMOXANE COCATALYSTS | ENICHEM S.P.A. (IT) | 1999-08-10 | — | — | US | disclosed |
| EP-0791607-A2 | Substituted metallocene catalyst for the (co)polymerization of olefins | ENICHEM S.p.A. (IT) | 1997-08-27 | — | — | EP | disclosed |