Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19206369 | 0.93 | TSHR (0.68) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16308941 | 0.91 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16308936 | 0.91 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16308929 | 0.91 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1322124 | 0.90 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12095074 | 0.89 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16308937 | 0.89 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19668584 | 0.88 | TSHR (0.89) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8962606 | 0.87 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8962684 | 0.86 | TSHR (0.68) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232376-B1 | BLEND CONTAINING ORGANOSILICON COMPOUND, PEROXIDE, HINDERED AMINE STABILIZER AND ANTIOXIDANTS | NIPPON UNICAR COMPANY LTD. (JP) | 2001-05-15 | — | — | US | disclosed |