Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962671 | 0.94 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27832270 | 0.90 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8962684 | 0.89 | TSHR (0.68) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7933425 | 0.87 | TSHR (0.74) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18037131 | 0.86 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2168904 | 0.85 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27812601 | 0.84 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1977194 | 0.83 | TSHR (1.00) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15200 | 0.83 | TSHR (1.00) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14995 | 0.83 | TSHR (1.00) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554706-A | LOW TEMPERATURE LIQUID CRYSTALS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0695770-A1 | COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-02-07 | — | — | EP | disclosed |