Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 1.00 |
| ▸ | CA1 | P00915 | 9/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924874 | 0.91 | CA2 (0.83) | CA2CA1CA12CA7CA9 | |
| SCHEMBL7933405 | 0.89 | CA2 (1.00) | CA2CA1CA4 | |
| SCHEMBL10973390 | 0.86 | CA2 (0.86) | CA2CA1CA4 | |
| SCHEMBL10973392 | 0.84 | CA2 (0.79) | CA2CA1CA4 | |
| SCHEMBL7924856 | 0.83 | CA2 (0.82) | CA2CA1CA12CA7CA9 | |
| SCHEMBL10938807 | 0.83 | CA2 (0.82) | CA2CA1CA4 | |
| SCHEMBL7937420 | 0.82 | CA2 (1.00) | CA2CA1CA12CA7CA9 | |
| SCHEMBL11118371 | 0.81 | CA2 (0.80) | CA2CA1CA4 | |
| SCHEMBL7931549 | 0.81 | CA2 (1.00) | CA2CA1 | |
| SCHEMBL10473859 | 0.81 | CA2 (1.00) | CA2CA1CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313155-B1 | Composition and method for treating macular disorders | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2001-11-06 | — | — | US | claimed |
| EP-0070239-A1 | Benzothiazolesulfonamide derivatives, their preparation and ophthalmic compositions containing said derivatives | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | claimed |
| EP-0070239-B1 | BENZOTHIAZOLESULFONAMIDE DERIVATIVES, THEIR PREPARATION AND OPHTHALMIC COMPOSITIONS CONTAINING SAID DERIVATIVES | MERCK & CO. INC. (US) | 1985-06-05 | — | — | EP | disclosed |
| US-4416890-A | GLAUCOMA TREATMENT | MERCK & CO., INC. (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0070239-A1 | Benzothiazolesulfonamide derivatives, their preparation and ophthalmic compositions containing said derivatives | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | disclosed |