Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756688 | 0.91 | MAPK1 (0.45) | MAPK1TDP1TRPA1CYP3A4MEN1 | |
| SCHEMBL7931281 | 0.78 | ALOX5 (0.39) | TDP1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL8929753 | 0.78 | MAPK1 (0.50) | MAPK1TDP1TRPA1CYP3A4MEN1 | |
| SCHEMBL7933674 | 0.72 | TDP1 (0.43) | MAPK1TDP1TRPA1CYP3A4MEN1 | |
| SCHEMBL7826908 | 0.70 | CYP4F2 (0.42) | MAPK1TDP1TRPA1CYP3A4KMT2A | |
| SCHEMBL9858564 | 0.69 | MAPK1 (0.50) | MAPK1TDP1TRPA1CYP3A4MAPT | |
| SCHEMBL10644838 | 0.69 | CYP4F2 (0.59) | MAPK1TDP1TRPA1CYP3A4KMT2A | |
| SCHEMBL25242327 | 0.68 | CYP4F2 (0.43) | MAPK1TDP1TRPA1CYP3A4KMT2A | |
| SCHEMBL25286184 | 0.68 | CYP4F2 (0.43) | MAPK1TDP1TRPA1CYP3A4KMT2A | |
| SCHEMBL9859287 | 0.67 | MAPK1 (0.54) | MAPK1TDP1TRPA1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | KLINTZ RALF (DE) | 2001-10-18 | — | — | US | disclosed |
| US-6239074-B1 | HERBICIDES, INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | CCR1, CCR6, CCR3 | MAPK1 3667/4885TDP1 1685/4885TRPA1 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.